Scientist, Immunology

Terray Therapeutics; Monrovia (CA); On-site; USD 120,000 - 175,000; Full time

Benefits offered by this job

Health, dental, and vision insurance

401k with a 3% safe harbor contribution

Stock option plan

Job summary

Initial Therapeutics, Inc. in Monrovia, CA, is seeking an experienced immunologist to join their cell assay team. This full-time role involves designing experiments and optimizing assays to support drug discovery efforts. Candidates must have a strong background in immunology and extensive experience with cellular techniques.

The position offers a competitive salary ranging from $120,000 to $175,000 annually, alongside substantial benefits including health, dental, and vision insurance, stock options, and a retirement plan. Join a rapidly growing biotech at the forefront of drug development.

Qualifications

• Strong background in immunology and immune signaling pathways.
• Extensive hands-on experience with cell culture and cellular assays.
• Proficiency in primary cell isolation and differentiation.

Responsibilities

• Design experiments to confirm mechanisms of action.
• Independently develop and optimize cell-based assays.
• Manage CROs for reagent development and testing.

Skills

Immunology

Cell culture

Flow cytometry

Data analysis

Education

PhD in immunology or related field

MSc with extensive experience

Tools

qPCR

RNAseq

ELISA

Luminex

Job description

Company Overview

Terray Therapeutics is a venture-backed biotechnology company where scientists and engineers build together to transform how small-molecule drugs are discovered and developed. By combining our nanotechnology, experimental science, machine learning, and automation, we leverage Terray’s ability to generate and learn from scale proprietary chemical data to discover novel medicines for patients in need.

At Terray, you will work alongside pioneers and experts in artificial intelligence, chemistry, drug discovery, automation, and nanotechnology in deeply interconnected workflows where computational and experimental teams continuously learn from one another. Our platform, EMMI (Experimentation Meets Machine Intelligence), powers iterative cycles of molecular design and wet-lab experimentation that rapidly improve our understanding of biochemical interactions and guide the next generation of discoveries.

Our teams support both an internal immunology pipeline and partnerships across a broad range of therapeutic areas. The work here is highly collaborative, fast-moving, and grounded in the belief that breakthroughs happen when strong science, thoughtful technology, and great people work closely together.

Position Summary

Terray Therapeutics is seeking a motivated, creative, and experienced immunologist to join our cell assay team. This role will be full-time onsite. The candidate will work with other scientists in the team to design experiments to evaluate the mechanism of action of hits from Terray’s proprietary EMMI platform and optimize assays to support program progression through hit-to-lead and lead optimization. The successful candidate will have a strong immunology background and understanding of immune signaling pathways along with demonstrated experience applying a broad range of cellular techniques to probe small molecule mechanism of action.

The core responsibilities of this position are:

• Review the literature to gain a comprehensive understanding of internal therapeutic targets of interest
• Design experiments to confirm the mechanism of action of small molecule hits from our binding and virtual screens in cells
• Independently develop, optimize, and run cell-based assays to profile on- and off-target activity of hits and hit series
• Adapt assays for medium to high-throughput screening and IC50 generation to support structure-activity-relationship understanding
• Manage CROs for reagent development and/or in vitro testing as needed
• Analyze and interpret experimental data and communicate results in project team meetings
• Interface with a multidisciplinary team (including chemists and computational scientists) as the immunology representative to drive decision-making
• Support organization of lab and equipment as needed

Experience and Qualifications

Given the company’s size, anticipated growth and fast-paced environment, the organization requires a scientist who is thoughtful, high energy, attentive to detail, and can work effectively with the biology team to further enhance our next-generation drug discovery capabilities.

Required Qualifications

• PhD in the field of immunology, molecular or cell biology, or related field with 3+ years of small molecule drug discovery experience
• Or MSc with 10+ years of small molecule drug discovery industry experience
• Strong background in immunology and immune signaling pathways
• Extensive hands-on experience with cell culture and cell-based assays, including reporter assays, gene and protein expression (eg: Flow cytometry, qPCR, RNAseq, Luminex, MSD, ELISA, Western) and intracellular techniques
• Proficiency in primary cell isolation, differentiation, culture and flow cytometry
• Experience establishing robust assays for small molecule dose responses and IC50 generation
• Excellent organizational, interpersonal and communication skills, and can thrive in a highly collaborative research environment
• Demonstrated technical proficiency, ability to troubleshoot to solve problems and to deliver high quality data

Candidates will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal-oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.

Compensation Details

$120,000 – $175,000 annually, depending on experience. Terray’s salary ranges are designed to be competitive and are benchmarked against market base salary plus bonus within our industry and market. We align pay to role scope, skill level, and impact.

Benefits

We invest heavily in benefits because taking care of our people matters. Our programs are benchmarked at the top of the Southern California market and designed to provide meaningful support across every stage of life. Benefits include participation in the Company’s stock option plan, a 3% retirement safe harbor contribution, fully paid health, dental, and vision insurance for our employees, spouse, partner, and families, as well as above-market life insurance, disability coverage, and much more to explore during the offer process.