Scientist III (Upstream)

US Tech Solutions; Worcester (MA); On-site; USD 60,000 - 100,000; Full time

Job summary

An innovative firm is seeking a dedicated Cell Culture/Expression Scientist to contribute to exciting protein expression projects. This role involves working in a collaborative environment to produce and screen biopharmaceutical candidates, requiring expertise in mammalian expression technologies and protein purification. Ideal candidates will have a strong background in life sciences and be adept at managing multiple tasks while staying current with scientific literature. Join a dynamic team that is committed to delivering cutting-edge therapies to patients and making a significant impact in the field of protein sciences.

Qualifications

• 3-5 years of laboratory experience for BS or 2-5 years for MS.
• Experience in transient protein expression in HEK293 or CHO cells.

Responsibilities

• Collaborate with project teams to drive innovation in protein sciences.
• Produce and screen recombinant biopharmaceutical candidates.

Skills

Cell Culture

Protein Expression

Mammalian Expression Technologies

Data Analysis

Communication Skills

Education

Bachelor's in Life Sciences

Master's in Life Sciences

Tools

SDS-PAGE

Western Blotting

ELISA

Flow Cytometry

Microscopy

Job description

BS with 3-5years, or MS with 2-5+ years of relevant laboratory experience will be considered for Scientist II or Scientist III

Description

• The Global Protein Sciences group collaborates with drug discovery project teams across therapeutic areas including Oncology, Immunology, and Neurology.
• We are seeking a cell culture/expression scientist to actively contribute in medium to pilot-scale protein expression activities in a centralized facility.
• Applicant should be proficient in mammalian (HEK and CHO) expression technologies. Familiarity with scale up to Wave Bioreactor would be beneficial. Protein purification experience a plus.
• Candidate should be self-motivated and must be able to work independently and also contribute in a team environment.
• Should stay current with applicable internal/external scientific literature and apply new information to successfully complete work assignments.
• Should be able to analyze and report data concisely and rigorously.
• Should possess excellent communication skills and be proficient in presenting in front of groups.
• Must be able to manage several tasks concurrently and be capable of adjusting to rapidly changing experimental priorities.

Key Responsibilities:

• Work collaboratively in a matrix with project teams and members of the Global Protein Sciences Group to drive innovation and deliver Client therapies to our patients.
• Impact projects through the production and screening of recombinant biopharmaceutical candidates.
• Demonstrate scientific excellence, work ethic, and dedication to team and project goals.

Qualifications:

• BS with 5-7+ years, or MS with 2-5+ years of relevant laboratory experience.
• The applicant¬タルs degree should be in the Life Sciences such as Biochemistry, Biology or Biomedical Engineering.
• Work history performing transient protein expression of IgG or similar biological molecules in HEK293 or CHO cells.

Preferred Qualifications:

• Experience performing SDS-PAGE, Western analysis, ELISA, flow cytometry, and microscopy and interpretation of protein analytical techniques such as SEC, MS, DLS, etc. are desirable
• Experience working with/implementation of automated laboratory workflows and instrumentation