Scientist III - siRNA platform development

Orion Group; Cambridge (MA); On-site; Full time

Job summary

Orion Group is seeking a Scientist III specializing in siRNA platform development for therapeutic applications in Cambridge, MA. This long-term contract role involves leading research in a cross-functional team, applying expertise to tackle scientific challenges in RNA-based therapies. Ideal candidates hold a PhD or a relevant Master's degree with a strong background in cell and molecular biology, capable of thriving in a fast-paced research environment.

Benefits

Medical insurance

Vision insurance

401(k)

Qualifications

• PhD or MS degree in molecular biology, cell biology, neuroscience, or biochemistry.
• Strong hands-on experience in cell and molecular biology.
• Ability to thrive in a dynamic, fast-paced research environment.

Responsibilities

• Lead research efforts within a team to advance siRNA platform development.
• Analyze and interpret multidisciplinary data.
• Contribute to internal reports and presentations.

Skills

Cell biology

Molecular biology

Biochemistry

Experimental design

Education

PhD in Cell Biology, Molecular Biology, or Biochemistry

Master's degree with significant experience

Job description

This range is provided by Orion Group. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$62.00/hr - $66.00/hr

Direct message the job poster from Orion Group

Scientist III - siRNA platform development for therapeutic applications.

Onsite in Cambridge, MA

1 year initial contract

Hourly Pay Rate: $62-66/hr (individual medical benefits available at a cost)

Position Overview:

Seeking a Contract Scientist to support the siRNA group within the Biotherapeutics and Genetic Medicine (BGM) department. This exciting long-term contract position offers the opportunity to contribute to the design and execution of cutting-edge experimental approaches to address key scientific challenges related to oligonucleotide therapeutics. The successful candidate will apply their scientific expertise to drive innovation, collaborate across teams, and support the development of novel RNA-based therapies.

Responsibilities:

• Lead research efforts within a cross-functional team to advance siRNA platform development for therapeutic applications.
• Resolve key project hurdles and assumptions utilizing available information and technical expertise
• Work autonomously to perform laboratory research or develop methods with minimal supervision, consistently delivering high-quality results.
• Demonstrate expertise in a wide range of relevant technologies and methodologies.
• Conceive and execute novel scientific research that achieves project goals
• Maintain high productivity in the laboratory, ensuring efficiency in experiment execution.
• Analyze and interpret multidisciplinary data, generating conclusions that drive future experimental directions.
• Contribute to internal reports, presentations, and potentially intellectual property filings.

Skills and Requirements:

• PhD (or equivalent experience) in Cell Biology, Molecular Biology, Biochemistry, or related field. Alternatively, a Master’s degree with 8 years of significant relevant experience may be considered.
• Strong hands-on experience in cell and molecular biology, including mammalian cell culture, mRNA isolation/quantitation by qPCR, sequencing (NGS/Sanger), and protein quantification by ELISA and western blot.
• Experience in oligonucleotide therapeutics is a plus.
• Familiarity with CNS disease models and DNA/RNA editing tools is highly desired.
• Outstanding aptitude for experimental design and execution, efficient assay development and creative problem solving.
• Ability to thrive in a dynamic, fast-paced research environment.
• Collaborative team player with excellent communication skills.

What are the top 3-5 skills, experience or education required for this position?

• PhD or MS degree in molecular biology, cell biology, neuroscience or biochemistry
• Industry experience in cell and molecular biology
• Good at mammalian cell culture
• Familiar with RNA extraction, qPCR, protein quantification with ELISA and Western
• Experience in oligonucleotide therapeutics is a plus

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Contract

Job function

• Job function

  Science and Research

• Industries

  Pharmaceutical Manufacturing, Biotechnology Research, and Medical Equipment Manufacturing

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Inferred from the description for this job

Medical insurance

Vision insurance

401(k)

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