Scientist II, Histology

Franklin Biolabs; King of Prussia (PA); On-site; USD 70,000 - 95,000; Full time

Benefits offered by this job

401(k)

401(k) Matching

Health insurance

Vision insurance

Health Savings Account

Flexible Spending Account

Paid Time-Off

Company Holidays

Personal Floating Holidays

Short-Term Disability

Long-Term Disability

Life and AD&D insurance

Job summary

Franklin Biolabs is seeking a Scientist II, Histology, to join the on-site Histology team in King of Prussia, PA. You will perform tissue processing, embedding, sectioning, and various staining methods, while ensuring GLP standards and proper documentation.

The role includes necropsy support and specimen archiving. The ideal candidate holds a BS in biology or life sciences with 5–7 years in histology, experience with automated staining systems, and knowledge of ALCOA/GLP guidelines.

Qualifications

• BS degree in biology, life sciences or related fields.
• 5-7 years of hands-on life science/histology experience.
• Experience with automated staining systems and other histology tools.
• Familiarity with ALCOA principles, FDA GLP regulations and related guidelines.

Responsibilities

• Perform tissue processing, embedding (paraffin and cryo), and sectioning per protocol.
• Conduct routine and specialized staining including H&E, IHC, ISH.
• Operate and maintain slide-scanning equipment and conduct image QC.
• Support necropsy procedures for small and large animals; act as prosector in NHP necropsies.
• Organize, label, and archive samples and slides per SOPs.
• Ensure GLP compliance, maintain documentation, participate in audits.
• Troubleshoot technical issues and suggest protocol improvements.

Skills

Anatomic knowledge

Organizational skills

Communication

Collaboration

Education

BS in biology/life sciences

Tools

Automated staining systems

Job description

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Scientist II, Histology

Histology Full Time King of Prussia, King of Prussia, PA, US

4 days ago Requisition ID: 1102

Franklin Biolabs emerges from the esteemed legacy of Dr. Jim Wilson's laboratory, a beacon of innovation in vector technology for over three decades. Building on this rich heritage, Franklin Biolabs is poised to redefine the landscape of the global genetic medicines industry. As a Contract Research Organization (CRO), Franklin Biolabs offers a comprehensive suite of services spanning from discovery through clinical manufacturing. Our goal is to empower our partners by providing unparalleled solutions that drive the advancement of genetic medicines. Leveraging decades of expertise and a commitment to excellence, we bridge the gap between groundbreaking research and ensuring that transformative therapies reach those who need them most.

The Histology team at Franklin Biolabs provides comprehensive histology and cell-morphology services—ranging from tissue processing and embedding to paraffin and cryo-sectioning, specialized staining (H&E, immunohistochemistry, in situ hybridization), slide scanning, and necropsy support for both small and large animal models. The Scientist II executes these core duties with minimal supervision, ensures proper organization and archiving of biological specimens, and maintains strict adherence to GLP regulations and quality-control standards. In addition, this role serves as a prosector for non GLP and GLP rodent and non-rodent necropsies.

Key Responsibilities:

• Perform routine tissue processing, embedding (paraffin and cryo), and sectioning according to protocol
• Conduct routine and specialized staining procedures, including H&E, immunohistochemistry (IHC), and in situ hybridization (ISH)
• Operate and maintain slide-scanning equipment; conduct image QC
• Support necropsy procedures for small and large animals; act as primary or secondary prosector in NHP necropsies
• Organize, label, and archive biological samples and slides in compliance with laboratory SOPs
• Ensure all activities meet GLP requirements, complete documentation, and participate in audits
• Troubleshoot technical issues and recommend protocol optimizations

Education and Experience:

• Minimum of BS degree in biology, life sciences and related fields.
• 5-7 years of hands-on experience in life science and histology related areas.
• Experience with automated staining systems and other histology tools.
• Experience preferred in conducting research and documentation in compliant with ALCOA (Attributable, Legible, Contemporaneous, Original, and Accurate) principles, FDA Good Laboratory Practices (GLP; 21CFR, Part 58) and other federal, state and local regulations and guidelines.

Certifications or Licenses:

• Histotechnician (HT) and/or Histotechnologist (HTL) certifications (preferred)

Knowledge, Skills and Abilities:

• Anatomic knowledge and skills to perform GLP compliant necropsies on rodents and large animals
• Good analytical and organizational skills.
• Self-directed individual with the ability to perform in a fast-paced environment with limited direction, competing priorities under tight deadlines.
• Ability to communicate clearly and effectively, both verbally and in writing, to interact with team members, clients, vendors and other third parties.
• Ability to collaborate effectively with individuals across various disciplines to ensure alignment.
• Ability to use digital communication tools (video conferencing, chat platforms etc.) to effectively collaborate with team members in hybrid and remote settings.

On-Site:

• This position requires full-time on-site presence at our Discovery Labs location.

Immunizations and Screenings:

• This position will require working with animals (e.g. Non-Human Primates, Rabbits, Rats, Mice).
• This position requires access to lab spaces.
• This position will require access to lab animal spaces.
• Essential for Closure: This position may be required to go on-site during company closures to sustain the life and care of animals/biological materials. Examples of company closures include snow days, special shutdowns, etc.
• Essential for Research: This position may be required to go on-site to perform their regular work functions related to continued research during periods of adjusted operations.

Vision:

• Ability to distinguish between different colors (normal color vision).
• Adequate near vision for reading documents or lab equipment.
• Ability to focus and maintain concentration in tasks for extended periods.
• Ability to work in environments with varying light conditions.

Company Benefits:

• 401(k)
• 401(k) Matching
• Health insurance
• Vision insurance
• Health Savings Account and Flexible Spending Account
• Paid Time-Off
• Company Paid Holidays
• Personal Floating Holidays
• Short-Term and Long-Term Disability
• Life and AD&D insurance (Group & Voluntary)