Scientist II, Bioanalytics

Vir Biotechnology; San Francisco (CA); Sur place; USD 116 000 - 146 000; Plein temps

Résumé du poste

Vir Biotechnology is seeking a detail-oriented Bioanalytical Scientist to join our Translational Development team in San Francisco. You will develop and implement bioanalytical methods to support large-molecule programs at preclinical and clinical stages, including immunochemistry assays and LC-MS/MS analysis.

This role emphasizes collaboration, data interpretation, and rigorous GLP/GCP-compliant practices across multiple programs, with at least four days on-site per week at our SF headquarters.

Qualifications

• PhD with 1+ years, MS with 6+ years, or BS with 8+ years of relevant industry experience.
• Experience in managing CROs for assay development/validation is a plus.
• Understanding of GLP/GCP in sample handling and analysis.

Responsabilités

• Develop and optimize bioanalytical methods for large-molecule programs.
• Coordinate method development and sample analysis with program timelines.
• Troubleshoot complex bioanalytical methods and implement robust solutions.
• Prepare and characterize assay reagents using standard biochemical techniques.
• Maintain documentation and present results in group settings.
• Perform routine instrument maintenance and calibration as needed.
• Collaborate with assay development team to meet project goals.

Connaissances

Bioanalysis

Immunochemistry

LC-MS/MS

GLP/GCP

Project oversight

Data analysis

Team collaboration

Formation

PhD (1+ year)

MS (6+ years)

BS (8+ years)

Outils

ELISA

MSD

Description du poste

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN ® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.

Vir Biotechnology has exclusive rights to the universal PRO-XTEN ® masking platform for oncology and infectious disease. PRO-XTEN ® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

THE OPPORTUNITY

Vir Biotechnology is seeking a detail-oriented, highly motivated Bioanalytical Scientist to join our Translational Development team.

In this role, you will develop and implement bioanalytical methods to support large-molecule programs at both preclinical and clinical stages. Responsibilities include designing and executing immunochemistry assays (e.g., ELISA, MSD, anti-drug antibody assays) and preparing samples for LC-MS/MS analysis. You will contribute to immunoassay development across multiple programs and analyze preclinical samples for drug concentrations and anti-drug antibodies.

This description outlines the primary responsibilities and requirements but is not exhaustive; additional related duties may be assigned as needed.

This position is based at our San Francisco headquarters, with an expectation of at least 4 days per week on site.

WHAT YOU'LL DO

• Develop and optimize bioanalytical methods to support large-molecule preclinical and clinical candidates, providing bioanalytical input across research and development stages.
• Plan and coordinate method development and sample analysis activities in alignment with program and development timelines.
• Troubleshoot and evaluate complex bioanalytical methods to identify and implement robust solutions.
• Prepare and characterize assay reagents using standard biochemical techniques (e.g., protein conjugation, concentration determination, UV/Vis spectrophotometry).
• Maintain thorough and timely documentation in electronic lab notebooks; compile, analyze, and interpret data.
• Present experimental plans and results in group and cross-functional settings to communicate assay development progress.
• Perform routine instrument maintenance, calibrations, and performance checks as needed.
• Collaborate closely with other assay development team members to achieve project and departmental goals.

WHO YOU ARE AND WHAT YOU BRING

• PhD with 1+ years, MS with 6+ years, or BS with 8+ years of relevant industry experience.
• Experience that combines hands-on laboratory work with project oversight; prior experience managing CROs for clinical and nonclinical assay development/validation is a plus.
• Demonstrated understanding of GLP/GCP principles as they pertain to sample handling and storage, bioanalytical assay development, sample analysis, and laboratory operations.
• Strong technical expertise with platforms used to characterize large-molecule therapeutics, including assays with complex handling and preparation (e.g., enzymatic, ligand-binding, cell-based assays, and LC-MS/MS assays) across a range of biological matrices (e.g., serum, plasma).
• Familiarity with PK/PD concepts and their application to assay design, selection, and range determination.
• Prior work in GCP/GLP/GMP environments is advantageous but not required.
• Prior work utilizing LC/MS/MS is advantageous but not required

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WHO WE ARE AND WHAT WE OFFER

The expected Salary range for this position is $116,000 to $146,000 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.

Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications.

Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics.

This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.

Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.

For hires based in the United States, Vir Biotechnology, participates in E-Verify .

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Vir Biotechnology’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.