Senior Scientist I, Drug Product & Device Development (Temporary)

Vir Biotechnology; San Francisco (CA); On-site; USD 105,000 - 131,000; Full time

Job summary

Vir Biotechnology in San Francisco is seeking a Senior Scientist I to lead formulation development and process optimization for parenteral antibodies and biologics. This role blends hands-on lab work with technical leadership across programs and external partners.

You will design DoE-based studies, guide tech transfer to contract manufacturers, and contribute to regulatory-ready documents. PhD with 5+ years (or equivalent) and lyophilization/prefilled-syringe experience are preferred; onsite 5

Qualifications

• PhD with 5+ years, Master’s with 8+ years, or Bachelor’s with 10+ years in biosciences or related.
• Expertise in formulation and drug product development for monoclonal antibodies and biologics; lyophilization and prefilled syringe experience preferred.
• Experience with experimental design (DoE), data analysis, and statistical programs for formulation screening and optimization.
• Strong knowledge of analytical methods for formulation assessments.
• Experience leading cross-functional teams and external collaborations.
• Experience authoring development reports and regulatory filings.

Responsibilities

• Scientific leadership of formulation development and process optimization for parenteral dosage forms of monoclonal antibodies and biologics.
• Design and execute in-house studies, including formulation screening, in-use stability studies, and analytical characterization using DoE.
• Provide technical direction and oversight for internal/external DP development and manufacturing activities, including data review and risk assessment.
• Lead tech transfer of manufacturing processes to contract manufacturers with cross-functional alignment.
• Author and review high-impact technical reports, regulatory submissions, and scientific publications.
• Represent Drug Product and Formulation and Device Development on cross-functional teams, contributing to strategy and timelines.
• Ensure scientific oversight for data from internal teams and CRO/CMO partners; uphold best practices.
• Drive continuous improvement and adopt new technologies to strengthen capabilities.

Skills

Formulation development

Lyophilization

DoE

Data analysis

Analytical methods

Education

PhD in Biosciences, Pharmaceutical Technology, Biochemistry, Chemistry, Chemical Engineering, or related

Master’s in biosciences or related field (5+ years experience required)

Bachelor’s in biosciences or related field (10+ years experience)

Tools

Statistical software

Job description

Senior Scientist I, Drug Product & Device Development (Temporary)

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN ® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.

Vir Biotechnology has exclusive rights to the universal PRO-XTEN ® masking platform for oncology and infectious disease. PRO-XTEN ® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

THE OPPORTUNITY

Vir Biotechnology is looking for an accomplished Temporary Senior Scientist I (12+ month contract to star) to help advance our Drug Product and Device Development group. In this impactful role, you will take on technical leadership for the development of both liquid and lyophilized formulations across multiple biologic modalities, including support for clinical-stage process development and manufacturing initiatives. You will serve as a scientific representative for Drug Product on cross-functional program teams, collaborating across departments and external partners to ensure the successful progression of pipeline assets from early discovery through late-stage development.

This role is a balanced mix of technical, hands-on laboratory work and leadership responsibilities, where you will independently design and manage formulation strategies for both internal and external projects while championing data-driven decision-making, process optimization, and cross-functional program support.

This Person will report to the Senior Director, Drug Product Process and Formulation

This role is located in our San Francisco headquarters with the expectation to be onsite 5 days a week

WHAT YOU'LL DO

• Scientific leadership of formulation development and process optimization for parenteral dosage forms of monoclonal antibodies and biologics, ensuring robustness, stability, and scalability
• Design and execute in-house laboratory studies, including formulation screening, in-use stability studies, and analytical characterization, leveraging advanced experimental designs (DoE) and statistical methods
• Provide technical direction and oversight for internal and external drug product development and manufacturing activities, including data review, trouble-shooting, and risk assessment
• Lead technical transfer of manufacturing processes at contract manufacturing organizations, managing cross-functional alignment and proactively addressing challenges
• Author and review high-impact technical reports, regulatory submissions, and scientific publications, ensuring clarity, accuracy, and regulatory compliance
• Represent Drug Product and Formulation and Device Development on cross-functional program teams, actively contributing to strategy, timelines, and issue resolution in collaboration with clinical, process development, analytical, quality, and regulatory stakeholders
• Ensure consistent scientific oversight for data generated by internal teams and contract research/manufacturing organizations, upholding best practices and industry standards
• Drive continuous improvement initiatives and implement new technologies or methodologies to strengthen group capabilities

WHO YOU ARE AND WHAT YOU BRING

• PhD with 5+ years , Master’s with 8+ years’ or Bachelor’s with 10+ years’ experience, in Biosciences, Pharmaceutical Technology, Biochemistry, Chemistry, Chemical Engineering, or a related discipline
• Demonstrated expertise in formulation and drug product development for monoclonal antibodies and biologics required; hands-on experience with lyophilization and prefilled syringe development strongly preferred
• Proficiency in experimental design (DoE), data analysis, and use of statistical programs for formulation screening and optimization.
• Strong working knowledge of analytical methods supporting formulation assessments
• Possess a solid understanding of pharmaceutical development, particularly as related to biological drug development
• Experience authoring development reports, batch records, SOPs, regulatory filings, or other documents
• Previous experience representing Drug Product and formulation on inter-disciplinary teams and with external collaborations
• Experience leading technical projects and mentoring junior team members

WHO WE ARE AND WHAT WE OFFER

The expected hourly range for this position is $76.00 to $95.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.

Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics.

This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.

For hires based in the United States, Vir Biotechnology, participates in E-Verify .

This position is based in our San Francisco headquarters with a requirement to be onsite at least 3 days per week.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Vir Biotechnology’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service‑connected disability.

A "recently separated veteran" means any veteran during the three‑year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.