Scientist I, Dermatology/Immunology

AbbVie Inc.; Cambridge, Northern (MA, KY); Hybrid; USD 110,000 - 170,000; Full time

Benefits offered by this job

Paid time off

Health insurance

401(k)

Job summary

AbbVie’s Immunology R&D Dermatology Discovery team at the Cambridge Research Center is seeking a Scientist to contribute to identifying novel therapeutics for inflammatory skin diseases. The role focuses on in vitro models with human translation, employing transcriptomics and multi-omics alongside wet-bench experiments.

The successful candidate will work in a fast-paced, collaborative environment, performing assays and data analysis while maintaining detailed records and ensuring compliance with

Qualifications

• Bachelor’s degree with 5 years of experience in biological sciences.
• Master’s degree with 2 years of experience is desired.

Responsibilities

• Sterile cell culture using cell lines, primary human and murine cells.
• Process and analyze ex-vivo human tissues for disease-relevant endpoints.
• Perform analyses using flow cytometry, qPCR, protein analyses (ELISA, MSD, multiplex), Western blotting, and microscopy.
• Develop and implement assays that monitor cellular processes.
• Analyze data using statistical methods and present findings.

Skills

Sterile cell culture

Flow cytometry

qPCR

Protein analyses

Western blotting

Microscopy

Data analysis

Scientific communication

Keratinocytes/ Fibroblasts experience

Education

Bachelor’s degree in molecular biology/immunology or related field

Master’s degree in a relevant field (desired)

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, Xand YouTube.

Job Description

AbbVie’s Immunology R&D organizationis looking fora highly motivatedScientist Ito join ourDermatologyDiscovery teamat the Cambridge Research Center in Cambridge, MA. This researcher willcontribute to the identification and validation of novel therapeutics for inflammatoryskindiseases.TheDermatology Discovery teamapplieshuman disease transcriptomic and multi-omicsdata setsin combination with wet-bench science to performmechanistic in vitro studieswith the overarching goalto elucidate disease-drivingmechanismsthat willadvance innovative therapeutic strategies. The successful candidate willplay a key role inthepreclinicalresearch team byconductingin vitro modelsfocusing on human translation to HS andPsO.

The ideal candidate is scientifically curious, collaborative,enthusiastic, skilled, anddedicated. This position requires passion, attention to detail, prior hands-on experience, and teamworkwithin a fast-paced drug discovery environment.

KeyResponsibilities:

• Sterile cell culture (cell lines and primaryhuman and murinecells)

• Process and analyze ex-vivo human tissues for disease-relevant endpoints

• Perform analyses using the following techniques:

1. Flow cytometry

2. Quantitative PCR

3. Protein analyses – ELISA, MSD and multiplex assays

4. Western blotting

5. Microscopy

• Develop and implement assays that monitor cellular processes

• Analyzedata using appropriate statistical methods and communicate findings through presentations and scientific discussions

• Maintain detailed experimental records and ensure compliance with electronic laboratory notebook

• Prior hands-on experience with keratinocytes, fibroblasts, and immune cells (Th17 T cell differentiation, macrophage polarization)is a plus

• Candidates with priorexperiencein complexhuman in vitro modelwill receive extra consideration

Qualifications

• Bachelor’s degree in molecular biology, immunology or other biological sciences (BS/BA)with 5 years of experience

• Master’s degree with 2 years of experience is desired

Key AbbVie Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance
• Learns fast, grasps the “essence” and can change course quickly
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others and nurtures innovation to make possibilities real

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible toparticipate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html