Scientist I, Cell and Molecular Biologist

AbbVie; North Chicago (IL); On-site; USD 110,000 - 150,000; Full time

Benefits offered by this job

Paid time off

401(k)

Job summary

AbbVie Oncology Discovery is seeking a highly motivated cancer cell biologist to support drug discovery programs focused on antibody-drug conjugates. You will develop and optimize pharmacological, biochemical and cell-based assays while collaborating with a multidisciplinary team to move programs from discovery toward preclinical development.

The role requires hands-on experience in molecular/cellular biology, assay development and data interpretation, with opportunities to contribute to

Qualifications

• Bachelor’s degree with 5 years of experience or Master’s with 2+ years in molecular/cellular biology or related field.
• Proficiency in tissue culture, biochemical in vitro assay development and molecular biology techniques (e.g., Western blotting/WES, ELISA, proliferation assays, FACS, lentivirus).
• Background in drug discovery, pharmacology and assay development.
• Strong organizational skills and proficiency with Excel, PowerPoint, GraphPad, FlowJo, etc.

Responsibilities

• Design and execute in vitro studies to assess antibody-drug conjugates.
• Analyze and interpret data; present to project team and propose follow-ups.
• Troubleshoot and optimize experimental procedures to advance programs.
• Contribute to data packages for publications, regulatory documents and patents.
• Work independently in a fast-paced, multi-tasking environment within a diverse team.
• Collaborate with cross-functional teams to progress programs from discovery to preclinical development.

Skills

Tissue culture

In vitro assay development

Molecular biology

Western blot/WES

ELISA

FACS

Lentivirus

Data analysis

Education

Bachelor’s degree in molecular/cellular biology

Master’s degree in related discipline

Tools

GraphPad

FlowJo

Excel

PowerPoint

Job description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn,Facebook,Instagram,XandYouTube.

Description:

AbbVie Oncology Discovery is seeking a highly motivated and experienced cancer cell biologist to support drug discovery projects in our in vitro cancer biology team with a focus on antibody-drug conjugates. The candidate will work closely with a team of experienced scientists to develop and optimize key pharmacological, biochemical and cell-based assays to support multiple programs.

Key Responsibilities:

• Design and execute in vitro studies to assess novel antibody-drug conjugates
• Analyze and interpret experiments and present data to the broader project team and group meetings. Propose relevant follow-up experiments as needed.
• Troubleshoot and/or optimize experimental procedures as needed to further the program goals.
• Contribute to the preparation of data packages for scientific publications, regulatory documents, and patent applications
• Work independently in a fast paced, multi-tasking environment as part of a diverse research team.
• Collaborate with cross-functional teams to advance programs from early discovery to preclinical development

Qualifications

Required:

• Bachelor’s Degree with 5 years of experience, or Master’s Degree with two years of experience in molecular/cellular biology, cancer biology, pharmacology or related discipline with significant research experience.
• Proficiency in tissue culture, cellular & biochemical in vitro assay development and molecular biology techniques (e.g Western blotting/WES, ELISA, proliferation assays, FACS, lentivirus)
• Background in drug discovery, pharmacology and assay development.
• Organizational skills and experience with computer programs, including Microsoft Excel, Powerpoint, GraphPad, FlowJo, etc.

Preferred:

• Understanding and application of methods of antibody characterization and/or antibody-drug conjugates.
• Knowledge and experience with a broad range of assays to characterize targeted protein degradation
• Familiarity and proficiency with available genomic/transcriptomic datasets (TCGA, DepMap, CCLE etc.)

Key Leadership Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the 'essence' and can change the course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces innovation and manages to reality.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this roleat thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on manyfactors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible toparticipate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount isearned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, and any other form ofcompensation and benefitsthat areallocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Company’s sole and absolutediscretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html