Scientist I - Biophysics and Formulation

Novo Nordisk A/S; Lexington (MA); On-site; USD 80,000 - 130,000; Full time

Job summary

An innovative company is seeking a highly motivated Scientist I to join its biophysics and formulation team in Lexington, Massachusetts. This role involves formulating and characterizing peptides, proteins, small molecules, and oligonucleotides, supporting therapeutic programs across various disease areas. You'll collaborate with cross-functional teams, utilize advanced biophysical characterization techniques, and stay updated with the latest drug delivery technologies. Join a culture that values collaboration, diversity, and making a real difference in patients' lives while enjoying a supportive work environment.

Benefits

Competitive compensation package

Support for healthy work-life balance

Inclusive culture

Opportunities for career development

Qualifications

• 12+ years of relevant experience required; advanced degrees may substitute years of experience.
• Strong knowledge in biophysical characterization and formulation development.

Responsibilities

• Design and select appropriate dosage forms for drug products.
• Collaborate with teams to ensure biophysical attributes are met.

Skills

Biophysical characterization

Formulation development

Drug delivery systems

Data analysis and interpretation

Project management

Scientific communication

Attention to detail

Education

BS/BA Degree

Advanced degree in relevant field

Tools

Electronic laboratory notebooks (ELN)

Solid state characterization equipment

Biophysical characterization equipment

Process analytical technologies

Job description

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Scientist I - Biophysics and Formulation

Facility: Data & AI

Location: Lexington, MA, US

About the Department

Our Boston Research & Development hub, anchored in the greater Boston area, brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown and Cambridge reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our greater Boston R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

The team is comprised of collaborative, diverse and passionate people who have a true sense of pride in their work and are committed to helping others grow and develop their careers. You’ll also have a platform to engage with key stakeholders on a global scale throughout the entire pipeline process. And while changing the future of diabetes, obesity and MASH treatment is no easy task, we also recognize the importance of an enjoyable workplace, which is why we’ve cultivated a culture of fun, ingenuity and innovation. Our competitive compensation package and support of a healthy work-life balance all add to a best-in-class employee experience. We are changing lives for a living. Are you ready to make a difference?

The Position

Novo Nordisk is seeking a highly motivated scientist to join its biophysics and formulation team in Lexington, Massachusetts. The candidate will be responsible for the formulation and characterization of peptides, proteins, small molecules, and oligonucleotides. This position will support therapeutic programs in multiple disease areas and will contribute to the development of novel drug delivery platforms.

Relationships

This position reports to the Head of Advanced Drug Delivery (Biophysics and Formulation).

Essential Functions

1. Utilize subject matter knowledge in biophysics, formulation, and drug delivery to design and select the appropriate dosage form for a drug product.
2. Collaborate with cross-functional teams to ensure the selected dosage form meets the desired biophysical attributes of the lead candidate and contribute to the early screening strategies and execution.
3. Consider factors such as chemical, biochemical, biological, medical, devices, patents, and commercial aspects when making formulation decisions.
4. Stay up-to-date with the latest advancements in biophysics and formulation-based drug delivery technologies and evaluate the potential benefits and applicability of new technologies to enhance drug delivery and formulation processes.
5. Provide recommendations on the acquisition and implementation of new technologies based on their potential impact and alignment with business objectives.
6. Collaborate with relevant stakeholders to ensure successful integration and utilization of new technologies into the pipeline.
7. Operate, maintain, and troubleshoot lab instruments such as solid state and biophysical characterization equipment and drug product manufacturing processes.
8. Conduct laboratory work in a safe, efficient manner that ensures a safe working environment for colleagues.
9. Implement automation strategies for performing high throughput biophysical screening.

Qualifications

1. BS/BA Degree with 12+ years’ relevant experience required; years of experience may be substituted by advanced degree(s) as deemed appropriate, degree within subject matter expertise preferred.
2. Strong knowledge and expertise in biophysical characterization, formulation development, and drug delivery systems required.
3. Demonstrated experience in evaluating and implementing new technologies in biophysics and formulation-based drug delivery required.
4. Proficient in data analysis and interpretation for drawing conclusions and making recommendations, including advanced statistical models, e.g., DoE.
5. Experience with digitalization and automation, including process analytical technologies.
6. Experience in project management and working collaboratively with cross-functional teams.
7. Excellent scientific communication skills and ability to engage with stakeholders effectively.
8. Strong attention to detail and ability to document experimental work with electronic laboratory notebooks (ELN).
9. General knowledge of cGMP, GLP, and regulatory requirements for pharmaceutical industries a plus.

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk, we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world, and we know that this is only possible with talented employees with diverse perspectives, backgrounds, and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve, and the communities we operate in. Together, we’re life changing.

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.