Scientist I - ADME Tox

LabRulez; Missouri; On-site; USD 75,000 - 95,000; Full time

Benefits offered by this job

Medical, dental, vision

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA Discovery Services in Missouri is seeking a Scientist I - ADME/Tox to advance analytical chemistry and LC-MS method development within a growing team. The role centers on developing LC-MS methods for ADME/DMPK and BioAnalysis, supporting study teams and ensuring high-quality data.

This position offers opportunities to mentor junior scientists and contribute to method validation and continuous improvement.

Qualifications

• 3+ years of direct LC-MS experience in a CRO or industry lab.
• Experience validating bioanalytical methods per FDA/ICH/OECD.
• Experience working in a Quality Management System.
• High-throughput analytical method development experience for small molecules.
• Experience leading R&D or innovation programs.
• Experience leading in human mammalian cell culture laboratories.
• Experience working with 384-well and 96-well plates.
• BS with 3+ years, MS with 2+ years, or PhD with 1+ years of relevant experience.
• Ability to work in the U.S. indefinitely without sponsorship.

Responsibilities

• Develop LC-MS methods for ADME/DMPK and BioAnalysis applications.
• Develop analytical methods to support project teams internally and externally.
• Troubleshoot and maintain Mass Spectrometers and HPLC units.
• Prepare and manage inventory of buffers, reagents, and finished goods.
• Provide solutions to complex problems and drive process improvements.
• Perform data and QC reviews within the department.
• Support validation of new methods contributing to service expansion.

Skills

LC-MS

Method Development

Quality Management

Team Leadership

Education

B.S. in Chemistry

M.S. or Ph.D. preferred

Tools

Sciex Instruments

Thermo Instruments

Job description

Scientific and Research Fellow, Analytical chemist, Liquid chromatography, Liquid chromatography-mass spectrometry

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

In over 35 years, Eurofins has grown from one laboratory in Nantes, France to 61,000 staff across a decentralised and entrepreneurial network of ca. 900 laboratories in 61 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2025, Eurofins generated total revenues of EUR 7.296 billion, and has been among the best performing stocks in Europe over the past 20 years.

Scientist I - ADME Tox

Job Description

Are you looking to grow your experience in the ADME-Tox space? Look no further! Come join our dynamic and growing team for a great opportunity. The Scientist Iwill support the Eurofins Discovery business in contract research services. This role requires applied experience and proven knowledge in analytical chemistry method development and analysis, with related experience in a contract research organization (CRO) or industry laboratory.

Here’s what you’ll do:

• Perform work in a laboratory setting and meets the physical job requirements of a lab role.
• Provide leadership and mentorship for junior scientists, and lab leadership through daily lab management, equipment management and lab planning.
• Performwork in a laboratory setting, meeting the physical job requirements of a lab role.
• DevelopLiquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK and BioAnalysis applications
• Developanalytical methods supporting project teams both internally and externally for new assay development.
• PerformTroubleshooting and Maintenance of Mass Spectrometers and HPLC units.
• Experience with Sciex® or Thermo High Resolution/ Accurate Mass Instrumentation is a plus.
• Prepareand manages inventory of buffers, reagents, semi-finished and finished goods.
• Providesolutions to more complex problems, identifies and initiates process improvements
• Performdata and report QC review within the department and may support the Study Director.
• Supportvalidation of new methods that contribute to expansion of service/product line, equipment, and data management systems.

Qualifications

The ideal candidate:

• 3+ years of of direct/demonstrated experience with Liquid Chromatography- Mass Spectrometry (LC-MS) in a contract research organization or industry laboratory in one or more of the following areas:
  • Bioanalytical Method Development for Small and/or Large Molecules
  • Drug Metabolism and Metabolite Identification w/ Structural Elucidation
  • Mass Spectrometry-Based Proteomics experimental design & execution
• Demonstrated experience with validation of bioanalytical methods in accordance with regulatory (FDA, ICH, OECD) guidelines.
• Experience working in a Quality Management System.
• Demonstrated proficiency in High-Throughput analytical method development for small molecules.
• Experience in leading and delivering results in R&D or innovation programs.
• Demonstrated experience leading in human mammalian cell culture laboratories.
• Demonstrated experience working with light-based readers with 384-well and 96-well plates.
• B.S. with 3 years of relevant experience
• M.S. with 2 years of relevant experience
• Ph.D. with 1 years of relevant experience
• Or an equivalent combination of education and experience
• Ability to work in the U.S. indefinitely without sponsorship or restriction

Additional Information

The position is full-time, Monday-Friday, 8 a.m.- 5 p.m., with overtime as needed. Candidates living within a commutable distance of St. Charles, MO are encouraged to apply.

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.