Scientist I

BioSpace; Frederick (MD); On-site; USD 94,000 - 134,000; Full time

Job summary

Leidos Biomedical Research, Inc. at Frederick National Laboratory for Cancer Research seeks a PhD scientist to design CRISPR-mediated experiments and oversee genetic studies in mammalian cells.

You will interface with collaborating investigators, assist in project management, and contribute to scientific manuscripts. The role requires strong molecular biology expertise, data analysis skills, and the ability to communicate complex results clearly.

Qualifications

• PhD required or equivalent from CHEA-acknowledged institution.
• Expertise in CRISPR/Cas9 and general molecular biology.
• Experience with data acquisition, management, and analysis.
• Strong written and oral communication; ability to produce documentation and manuscripts.
• Demonstrated research accomplishments such as peer-reviewed publications or conference posters.

Responsibilities

• Design CRISPR-mediated experiments including knockouts and knock-ins.
• Collaborate with investigators, provide guidance, and respond to queries.
• Assist the laboratory director with project management and activity reporting.
• Perform CRISPR experiments in mammalian cells (knockouts, clonal lines, genetic screens).
• Conduct Illumina-based targeted amplicon sequencing.
• Clone plasmid constructs as needed.
• Contribute to manuscripts from GMC-led and supported projects.

Skills

CRISPR/Cas9

Molecular biology

Data analysis

Communication

Project management

Security clearance eligibility

Education

PhD degree

Tools

Python

HPC

Job description

Job ID: req4690

Employee Type: exempt full-time

Division: Laboratory Animal Science Program

Facility: Frederick: Ft Detrick

Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

Program Description

The Laboratory & Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for laboratory and animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of husbandry, veterinary, state-of-the-art technology, and pre-clinical scientific services.

Key Roles/Responsibilities

• Design CRISPR-mediated experiments which include, but not limited to, gene knockouts, gene knock-ins, custom targeted libraries
• Interface with the collaborating investigators on projects – providing guidance, consultation, and responding to queries in a timely manner
• Assist the laboratory director in project management and generating activity reports
• Perform CRISPR-mediated experiments in mammalian cells – gene knockouts, clonal cell line generation, and genetic screens
• Illumina-based targeted amplicon sequencing
• Clone plasmid constructs when needed
• Contribute to manuscripts from both projects led by the GMC as well as supported by the GMC

Basic Qualifications

• Possession of a PhD degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA). Foreign degrees must be evaluated for U.S. equivalency
• Fundamental understanding and expertise in the CRISPR/Cas9 technology as well as general molecular biology
• Expertise in computer-based data acquisition, management, and data analysis
• Ability to plan, conduct, troubleshoot, and optimize scientific experiments
• Extensive communication and presentation skills, ability to prepare comprehensive informative project documentation and other written deliverables, such as manuscripts, meeting abstracts, etc.
• Prior research accomplishments documented e.g. in the form of significant publications in peer-reviewed journals, meeting poster presentations, invited talks, and other evidences of scientific achievements
• Ability to obtain and maintain a security clearance

Preferred Qualifications

• Software programming and development in python
• Experience running scripts and code on a high-performance computing (HPC) platform
• Well-developed self-organization, project planning and time management skills

JOB HAZARDS

• This position is subject to working with or has the potential for exposure to infectious material, requiring medical clearance and immunizations

Commitment to Non-Discrimination

All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, color, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.

Pay And Benefits

Pay and benefits are fundamental to any career decision. That's why we craft compensation packages that reflect the importance of the work we do for our customers. Employment benefits include competitive compensation, Health and Wellness programs, Income Protection, Paid Leave and Retirement. More details are available here

93,800.00 - 134,285.00 USD

The posted pay range for this job is a general guideline and not a guarantee of compensation or salary. Additional factors considered in extending an offer include, but are not limited to, responsibilities of the job, education, experience, knowledge, skills, and abilities as well as internal equity, and alignment with market data.

The salary range posted is a full-time equivalent salary and will vary depending on scheduled hours for part time positions