Scientist, Functional Genomics

BioSpace; Englewood (NJ); On-site; USD 135,000 - 175,000; Full time

Job summary

ICR is dedicated to solving some of the most challenging problems in aging and age-related disease. We're looking for talented scientists to join our Functional Genomics group, tasked with going from SNP to phenotype by connecting genomic variants with organismic-level symptoms through molecular, cellular, tissue and animal models.

You'll research the functional impact of SNPs, manage CRO projects, collaborate with other ICR scientists, and identify potentially actionable targets for therapeutic

Qualifications

• PhD in Biomedical Sciences required.
• Experience with modern molecular and cellular biology techniques.
• Experience with iPSCs and iPSC differentiation protocols preferred; mammalian cell culture required.
• Experience creating and validating stem cell-derived disease models.

Responsibilities

• Research the functional impact of SNPs on protein or cellular function.
• Project manage outsourced CRO work to maximize productivity.
• Collaborate with Translational Bioinformatics and Genomics teams to solve problems.
• Identify actionable targets for therapeutic development.

Skills

Molecular biology techniques

iPSCs & differentiation

Mammalian cell culture

Programming (Python)

Education

PhD in Biomedical Sciences

Tools

Python

Job description

ICR is dedicated to solving some of the most challenging problems in aging and age-related disease. We're looking for talented scientists to join our Functional Genomics group. Tasked with going \"from SNP to phenotype,\" our Functional Genomics scientists connect genomic variants with organismic-level symptoms through molecular, cellular, tissue and animal models.

With ICR, you'll get to:

• Research the potential functional impact of any given SNP on protein or cellular function: from RNA to protein to cell to systems-level analysis including work on known disease-associated SNPs and VUSs in the context of various human primary and iPSC-derived cell types
• Project manage out-sourced work with CROs to maximize your productivity
• Collaborate with other ICR scientists and groups, including Translational Bioinformatics and Genomics, to solve complex human medical mysteries
• Identify potentially actionable targets for therapeutic development

• PhD in Biomedical Sciences
• In-depth knowledge of and experience with modern molecular and cellular biology techniques, preferably experience doing functional genomics
• Experience with iPSCs and iPSC differentiation protocols preferred, but mammalian cell culture experience is a must
• Experience creating and validating stem cell-derived disease models
• Programming experience (Python preferred)

And You'll Need

• The ability to work in the United States without sponsorship
• To have an easygoing, hard-working personality

Salary

Starting base pay range: $135,000/yr - $175,000/yr

Starting additional compensation range: $7,500/yr - $17,500/yr

Starting position title and compensation are commensurate with experience.