Scientist, Functional Genomics

BioSpace; Englewood (NJ); Sur place; USD 135 000 - 175 000; Plein temps

Résumé du poste

ICR is seeking talented scientists to join the Functional Genomics group to connect genomic variants with organismic-level symptoms through molecular, cellular, tissue and animal models.

The role involves researching the functional impact of SNPs, coordinating CRO projects, and collaborating with Translational Bioinformatics and Genomics to uncover actionable therapeutic targets.

Qualifications

• PhD in Biomedical Sciences.
• In-depth knowledge of modern molecular and cellular biology techniques, preferably functional genomics.
• Experience with iPSCs and iPSC differentiation protocols, but mammalian cell culture is a must.
• Experience creating and validating stem cell-derived disease models.
• Programming experience (Python preferred).

Responsabilités

• Research the functional impact of SNPs on protein or cellular function from RNA to protein to cell to systems level.
• Project manage outsourced work with CROs to maximize productivity.
• Collaborate with other ICR scientists to solve complex human medical mysteries.
• Identify potentially actionable targets for therapeutic development.

Connaissances

Molecular biology techniques

iPSC / stem cell models

Mammalian cell culture

Python

Formation

PhD in Biomedical Sciences

Outils

Python

Description du poste

ICR is dedicated to solving some of the most challenging problems in aging and age-related disease. We're looking for talented scientists to join our Functional Genomics group. Tasked with going "from SNP to phenotype," our Functional Genomics scientists connect genomic variants with organismic-level symptoms through molecular, cellular, tissue and animal models.

With ICR, you'll get to:

• Research the potential functional impact of any given SNP on protein or cellular function: from RNA to protein to cell to systems-level analysis including work on known disease-associated SNPs and VUSs in the context of various human primary and iPSC-derived cell types


• Project manage outsourced work with CROs to maximize your productivity


• Collaborate with other ICR scientists and groups, including Translational Bioinformatics and Genomics, to solve complex human medical mysteries


• Identify potentially actionable targets for therapeutic development

Requirements

• PhD in Biomedical Sciences


• In-depth knowledge of and experience with modern molecular and cellular biology techniques, preferably experience doing functional genomics


• Experience with iPSCs and iPSC differentiation protocols preferred, but mammalian cell culture experience is a must


• Experience creating and validating stem cell-derived disease models


• Programming Experience (Python Preferred)


• The ability to work in the United States without sponsorship


• To have an easygoing, hard-working personality

Salary

• Starting base pay range: $135,000/yr - $175,000/yr


• Starting additional compensation range: $7,500/yr - $17,500/yr


• Starting position title and compensation are commensurate with experience.