Scientist, Functional Genomics

BioSpace; Englewood (NJ); On-site; USD 135,000 - 175,000; Full time

Job summary

ICR invites talented scientists to join our Functional Genomics group to solve aging and age-related disease. We move from SNP to phenotype, connecting genomic variants with organismic symptoms through molecular, cellular, tissue and animal models.

You will research SNP effects, manage CRO projects, collaborate with Translational Bioinformatics and Genomics, and help identify targets for therapeutic development. This role requires a PhD and experience with molecular biology, iPSCs, and Python.

Qualifications

• PhD in Biomedical Sciences.
• In-depth knowledge of and experience with modern molecular and cellular biology techniques, preferably experience doing functional genomics.
• Experience with iPSCs and iPSC differentiation protocols preferred, but mammalian cell culture experience is a must
• Experience creating and validating stem cell-derived disease models.
• Programming experience (Python preferred).

Responsibilities

• Research the potential functional impact of SNPs on protein or cellular function using various models.
• Project manage outsourced work with CROs to maximize productivity.
• Collaborate with other ICR scientists and groups to solve complex human medical mysteries.
• Identify potentially actionable targets for therapeutic development.

Skills

Python

Mammalian cell culture

Functional genomics

Stem cell differentiation protocols

Education

PhD in Biomedical Sciences

Tools

iPSC differentiation protocols

Job description

ICR is dedicated to solving some of the most challenging problems in aging and age-related disease. We’re looking for talented scientists to join our Functional Genomics group. Tasked with going "from SNP to phenotype," our Functional Genomics scientists connect genomic variants with organismic-level symptoms through molecular, cellular, tissue and animal models.

With ICR, you’ll get to:

• Research the potential functional impact of any given SNP on protein or cellular function: from RNA to protein to cell to systems‑level analysis including work on known disease‑associated SNPs and VUSs in the context of various human primary and iPSC‑derived cell types
• Project manage outsourced work with CROs to maximize your productivity
• Collaborate with other ICR scientists and groups, including Translational Bioinformatics and Genomics, to solve complex human medical mysteries
• Identify potentially actionable targets for therapeutic development

Please Apply If You Have

• PhD in Biomedical Sciences
• In‑depth knowledge of and experience with modern molecular and cellular biology techniques, preferably experience doing functional genomics
• Experience with iPSCs and iPSC differentiation protocols preferred, but mammalian cell culture experience is a must
• Experience creating and validating stem cell‑derived disease models
• Programming experience (Python preferred)
• Even if you don’t have all of these skills, please apply

And You’ll Need

• The ability to work in the United States without sponsorship
• To have an easygoing, hard‑working personality

Salary

Starting base pay range: $135,000/yr - $175,000/yr

Starting additional compensation range: $7,500/yr - $17,500/yr

Starting position title and compensation are commensurate with experience.