Scientist/Engineer – Retinal Prosthesis & Vision Restoration (Ex-vivo and rodent neuromodulatio[...]

Cahira Technologies; Boston (MA); On-site; USD 100,000 - 300,000; Full time

Job summary

A technology company based in Boston is seeking a Scientist/Engineer to join their bioengineering group focused on developing injectable, wireless nano-implants to restore eyesight. The ideal candidate will have a PhD in a relevant field and hands-on experience with small-animal ophthalmology. This is a full-time entry-level position offering a salary range of $100,000 to $300,000.

Qualifications

• PhD in neuroscience, vision science, or bioengineering required.
• Experience with rodent ocular surgeries necessary.
• Familiarity with electrophysiology techniques is essential.

Responsibilities

• Demonstrate application of injectable, wireless nano-implants.
• Conduct pre-clinical experiments for retinal prosthesis.
• Characterize efficacy and safety in rodent models.

Skills

PhD in relevant field

Hands-on experience with small-animal ophthalmology

Experience with rodent models

Hands-on experience with ocular surgeries

Experience with retinal electrophysiology

Data analysis and programming skills

Education

PhD in neuroscience or bioengineering

Tools

MATLAB

Python

Optical coherence tomography

Job description

Scientist/Engineer – Retinal Prosthesis & Vision Restoration (Ex-vivo and rodent neuromodulation, electrophysiology, behavior)

Join to apply for the Scientist/Engineer – Retinal Prosthesis & Vision Restoration (Ex-vivo and rodent neuromodulation, electrophysiology, behavior) role at Cahira Technologies

Scientist/Engineer – Retinal Prosthesis & Vision Restoration (Ex-vivo and rodent neuromodulation, electrophysiology, behavior)

Join to apply for the Scientist/Engineer – Retinal Prosthesis & Vision Restoration (Ex-vivo and rodent neuromodulation, electrophysiology, behavior) role at Cahira Technologies

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MIT Professor & Founder of Cahira Technologies Inc.

About the company

Cahira Technologies Inc is an MIT spinoff company (https://www.linkedin.com/company/cahiratech/). We have built the multiple award-winning technology of the world’s first autonomous and non-surgical neural implants: novel sub-cellular sized wireless electronic devices that seamlessly integrate with the neurons or other biological cells, enabling brain-computer symbiosis beyond conventional brain-computer interfaces. Join us in our exciting journey to define the future of neurotech!

About the role

We are building a bioengineering group to demonstrate the application of our injectable, wireless nano-implants to restore eyesight without surgery. This includes demonstrations of electrical neuromodulation using these devices in retinal explants and characterizations through multi-electrode array (MEA)/patch-clamp electrophysiology followed by in vivo tests in rodent models for efficacy (electrophysiology and behavior) and safety. This team will be responsible for end-to-end execution of all pre-clinical experiments required to bring our retinal prosthesis to IDE-enabling stage.

Qualifications

Required:

• PhD in neuroscience, vision science, neuro-engineering, biology, bioengineering, biomedical engineering or relevant field
• Hands-on experience with small-animal ophthalmology and retinal prosthesis for electrical stimulation such as bionic eye, photovoltaic implant, wired implant, sub-retinal or epi-retinal implant, injectable neuro-prosthesis, nanoparticles etc.
• Hands-on experience with rodent models such as Retinitis Pigmentosa (RP), Age-related Macular Degeneration (AMD) (rd1, rd10, RCS, S334ter etc)
• Hands-on experience with rodent (mouse/rats) ocular surgery such as retina isolation and injections such as intravitreal/suprachoroidal/sub-retinal/ subtenon injections
• Hands-on experience with retinal electrophysiology (multi-electrode array (MEA) or patch clamping) ex vivo in isolated retina
• Hands-on experience with in vivo electrophysiology such as measuring visual evoked potential and electroretinogram (ERG)
• Hands-on experience with characterizing acuity and resolution through methods such as pattern visual-evoked-potential (VEP) grating-acuity assay, optokinetic/optomotor reflex (OKR) test
• Hands-on experience with behavioral vision assays and tests such as pupillary light reflex, light/dark box, water-maze tests
• Hands-on experience in preparing retinal flat-mounts & cryo-sections; performing histology, immunostaining and confocal microscopy.

Preferred Experience:

• Experience with data analysis, statistical modeling and programming skills such as MATLAB/Python/COMSOL
• Experience in building optical equipment
• Experience in operating fundus camera & optical coherence tomography (OCT)
• Experience with optogenetics

Important: Please include a separate section titled "Skills" in your CV, clearly listing your in vivo, in vitro, and other relevant scientific/technical competencies and provide a full list of publications.

Seniority level

• Seniority level

  Entry level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Biotechnology Research, Medical Equipment Manufacturing, and Nanotechnology Research

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