Scientist, Cellular Resilience

AstraZeneca; Waltham (MA); On-site; USD 75,000 - 110,000; Full time

Job summary

AstraZeneca’s Aging Research Group in Cambridge area seeks a Scientist to join our efforts in extending healthspan. You will design and execute cell-based assays to support drug development of biologics and small molecules, contributing to cellular resilience in aging.

The role emphasizes collaboration, data interpretation, and clear communication with project teams as we advance pre-clinical programs in a fast-paced, cutting-edge environment.

Qualifications

• Bachelor’s or Master’s degree or equivalent experience with a minimum of 3 years post-graduation research experience.
• Experience in designing, executing, and interpreting cell-based assays.
• Outstanding communication and interpersonal skills with the ability to build effective relationships in a small team setting.
• Excellent analytical and problem-solving skills.

Responsibilities

• Collaborate with project teams to generate pre-clinical data packages.
• Design and execute in vitro experiments to assess intervention of the cellular aging process, with an emphasis on signaling pathways.
• Troubleshoot and optimize cell-based assays for internal and external transfer.
• Support ex vivo activities to complement CRO-run in vivo studies.
• Analyze and interpret experimental data, and present findings to internal stakeholders.
• Stay current with scientific literature and emerging technologies in the field of aging.

Skills

Cell-based assays

Communication skills

Interpersonal skills

Analytical thinking

Problem-solving

Education

Bachelor’s or Master’s degree or equivalent experience

Job description

At AstraZeneca, we're embarking on an exciting new frontier in medical science – the quest to extend human healthspan. Our newly formed Aging Research Group is at the forefront of this groundbreaking initiative, aiming to develop innovative therapeutics that not only add years to life but life to years. We are seeking a highly motivated Scientist to join dynamic team. As a key member of our group, you'll play a pivotal role in conducting assays to support drug development of biologics and small molecule compounds that support cellular resilience throughout the aging process.

At AstraZeneca, you'll have the opportunity to make a significant impact on the future of healthcare while working in a collaborative environment at the cutting edge of research. The ideal candidate will thrive in this setting, contributing to our growth trajectory as we build our evolving team.

Key Responsibilities

• Collaborate with project teams to generate pre-clinical data packages
• Design and execute in vitro experiments to assess intervention of the cellular aging process, with an emphasis on signaling pathways
• Troubleshoot and optimize cell-based assays for internal and external transfer
• Support ex vivo activities to complement CRO-run in vivo studies
• Analyze and interpret experimental data, and present findings to internal stakeholders
• Stay current with scientific literature and emerging technologies in the field of aging

Qualifications

• Bachelor’s or Master’s degree or equivalent experience with a minimum of 3 years post-graduation research experience
• Experience in designing, executing, and interpreting cell-based assays
• Outstanding communication and interpersonal skills with the ability to build effective relationships in a small team setting
• Excellent analytical and problem-solving skills

Desired Skills And Attributes

• Broad knowledge of cellular growth/stress pathways
• Strong molecular and cell biology skills with ability to intuitively troubleshoot and optimize complex assays
• Experience with biologics
• Highly self-driven with the ability to work both independently and part of a team
• Adaptable and comfortable with changing priorities in a fast-paced research environment

As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026. Find out more information here: Kendall Square Press Release

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.