Scientist - Cell Therapy Process Development

Insight Global; Lower Gwynedd Township (Montgomery County); On-site; USD 80,000 - 100,000; Full time

Benefits offered by this job

10 PTO days

6 paid sick days

Medical benefits

401K plans

Job summary

A leading pharmaceutical company located in Spring House, PA is seeking a Scientist for their Cell Therapy Process Development team. Responsibilities include designing and executing development studies, improving manufacturing outcomes, and supporting technology transfer. Candidates should have a Bachelor’s degree and at least 2 years of relevant process development experience. This contract position offers competitive compensation with opportunities for permanency.

Qualifications

• Minimum of 2 years of experience in process development for Cell Therapy.
• Hands-on experience with equipment used in process development.
• Strong understanding of CAR-T manufacturing processes.

Responsibilities

• Design and execute process development studies for T-cell therapies.
• Investigate improvements to current processes for T-cell selection.
• Support technology transfer activities and write necessary documentation.

Skills

Process development experience

Primary cell culture

Aseptic cell processing technique

Education

Bachelor's Degree in related field

Job description

Scientist - Cell Therapy Process Development

Base pay range: $80,000.00/yr - $100,000.00/yr

Location: Spring House, PA

Overview

Our client, a large pharmaceutical company, is seeking a Scientist to join the Process Development team within the Cell Therapy Development organization. The role focuses on CAR-T cell manufacturing, with approximately 80% of time spent in the lab setting up and running automation instruments for T cell manufacturing (primarily Prodigy), performing cell manipulation, sampling, and ensuring equipment operates correctly. The position emphasizes process development in CAR-T and its transfer to manufacturing.

Responsibilities

• Design and execute process development studies using sound scientific and engineering principles to develop and improve unit operations used for production of autologous T-cell therapies.
• Identify, critically assess and evaluate opportunities to improve manufacturing outcomes (e.g., success rate, throughput, cost, process time, and product quality).
• Lead or contribute to the design and execution of phase-appropriate process development study plans, identifying process parameters and ranges for optimal experimental design.
• Investigate improvements to current processes for T-cell selection, activation, transduction, and expansion and assess impact on critical quality attributes.
• Author reports detailing experimental work, results, protocols, technical reports, and SOPs.
• Support technology transfer activities, write protocols and reports, and coordinate activities to support successful manufacturing.

Qualifications

• Minimum of a Bachelor’s Degree in a related field.
• Minimum of 2 years of process development experience for Cell Therapy or CAR-T manufacturing.
• Hands-on experience with equipment and unit operations used in process development and manufacture of cell therapy products.
• Primary cell culture experience.
• Aseptic cell processing technique.

Compensation and Benefits

Salary: $80,000-$100,000 (flexible based on experience)

Hours: Monday-Friday, 8:00am-5:00pm

Hiring Method: Multiyear contract – After 1 year on contract, opportunity to apply for a permanent role or have contract renewed for another year

PTO: 10 PTO days, 6 paid sick days annually, and paid holidays

Benefits: Medical, Dental, Vision, and 401K plans available

Note: Exact compensation may vary based on several factors, including skills, experience, and education.

Additional Information

• Seniority level: Mid-Senior level
• Employment type: Contract
• Job function: Research
• Industries: Pharmaceutical Manufacturing

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