Scientist - Cell Biology & Toxicology

Rose International; South San Francisco (CA); On-site; USD 65,000 - 90,000; Full time

Job summary

Rose International is seeking a Scientist I/II for the Investigative Toxicology group at our South San Francisco campus. The role focuses on ex vivo and in vitro safety assessments across discovery and development, using a broad toolkit of biological assays and technologies.

Strong communication and collaboration are essential for cross-team contributions. The ideal candidate will enjoy learning across multiple toxicology modalities, contribute to project reports, and thrive in a

Qualifications

• Bachelor's degree in pharmacology, pharmaceutical science, biology, bioengineering, chemistry or related discipline is required.
• Master's degree is desirable but not required.

Responsibilities

• Provide scientific and technical support to assays and platforms used by the Investigative Toxicology group.
• Perform experiments including immortalized and primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry.
• Maintain documentation of protocols and results; write protocols and contribute to final reports.
• Adhere to SOPs to ensure study integrity and quality.
• Work with minimal supervision for routine methods and studies.

Skills

Lab experience

Data analysis

Presentation skills

Collaboration

Hypothesis-driven research

Education

Bachelor's degree in life sciences

Master's degree (desirable)

Tools

Luminex/ELISAs

Flow cytometry

Confocal microscopy

High-content screening

Gene expression analysis

Job description

Required Education

• Bachelor's (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required;

Preferred Education

• Master's (MS) degree is desirable but not required.

Required Skills

• 1-3+ years of laboratory experience with hypothesis-driven research.
• Ability to analyze, integrate, and present data in a presentation is required.

Role Will Involve

• Sitting or standing for extended periods.
• Performing repetitive tasks such as cell culture, pipetting and labeling tubes.
• Collaboration across the Investigative Toxicology team and with key stakeholders.
• Work with potentially hazardous materials including (but not limited to): chemotherapeutics, biological hazards, and human primary cells.

Preferred Skills

• Experience with complex in-vitro model systems is highly desired.
• Experience with immortalized and/or primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry is highly desired.

Summary

Client has an open Scientist I/II position in the Investigative Toxicology group within the department of Translational Safety located in our South San Francisco campus. The Investigative Toxicology group’s goal is to use ex vivo and in vitro tools to assess safety liabilities and mechanisms of toxicities observed pre-clinically to support the entire portfolio spanning discovery through development. This laboratory-based role involves performing, qualifying, and implementing biological assays and technologies to support the Investigative Toxicology group. This is an ideal position for a researcher who is enthusiastic about learning and contributing to projects with a broad range of techniques. As such the position requires excellent communication and collaboration skills, a desire to learn about and integrate multiple aspects of drug toxicity, and a passion for lab-based research.

Responsibilities

• Candidate will provide scientific and technical support to assays and platforms supported by the Investigative Toxicology group by:
• Performing experiments involving: immortalized and primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry. Experience with these methodologies is desirable, but not required.
• Maintaining documentation related to protocol execution and results.
• Writing protocols and contributing to final reports as appropriate.
• Adhering to departmental SOPs to ensure study integrity and quality.
• Conducting experiments with a high level of independence and initiative.
• Performing tasks with minimal direct supervision for routine methods and studies commonly employed by the team.
• Only those lawfully authorized to work in the designated country associated with the position will be considered.
• Please note that all Position start dates and duration are estimates and may be reduced or lengthened based upon a client’s business needs and requirements.

About Rose

• Founded in 1993
• Office Locations Across the U.S.
• 150+ Clients: Corporations and Government Agencies
• Employee Oriented Company
• Challenging Assignments Across the U.S.
• Continuous Professional Development

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