Scientist, Biologics Purification

AbbVie; North Chicago (IL); On-site; USD 85,000 - 162,000; Full time

Job summary

AbbVie’s Biologics Discovery Sciences group seeks a scientist specializing in Biologics Purification to drive high-purity multispecific antibody candidates. You will lead purification campaigns, design downstream strategies, and apply analytical methods to support in vitro and in vivo studies.

Collaboration across teams is essential. The role emphasizes data-driven decisions, scientific innovation, and effective communication of complex concepts to diverse audiences as part of a fast-moving

Qualifications

• BS or MS in Biochemistry, Biophysics, Biomedical, Chemical Engineering, or a related field with typically 5–7 years (BS) or 2–5 years (MS) of experience.
• Hands-on experience operating AKTA chromatography systems and Unicorn software.
• Strong foundation in analytical characterization techniques including HPLC, gel electrophoresis, ELISA, mass spectrometry.

Responsibilities

• Lead end-to-end purification campaigns at production-based scales for high-quality multispecific antibody biologics.
• Design and optimize downstream purification strategies using chromatography techniques.
• Apply analytics to characterize molecules, process intermediates, impurities, and final candidates for data-driven decisions.
• Drive process improvement by identifying novel approaches in downstream biologics development workflows.
• Collaborate with multidisciplinary teams to translate process insights into results for project progression.
• Present scientific findings clearly to diverse audiences to support project progression.

Skills

AKTA chromatography

Unicorn software

HPLC

Mass spectrometry

Education

Biochem/biophysics/biomedical/chemical eng. (BS or MS)

Tools

AKTA

Unicorn software

Job description

• Compensation: USD 84,500 - USD 162,000 - yearly

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Job Description

Join AbbVie’s Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Youwill leverage yourexpertisetodeliver high-puritymulti-specific antibody-based biologic candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.).

Key Responsibilities

• Leadend-to-end purification campaignsat production-based scalesfordeliveryof high-qualitymulti-specificantibody biologics to support critical researcheffortsandprogramdecisions
• Design and optimize downstream purification strategies using advanced chromatographytechniquestoremove process impurities, mitigate product liabilities, and achieve target quality attributes
• Apply deep analytical expertise to characterize molecules, process intermediates, impurities, and final drug candidates, enabling data-driven process decisions
• Drive scientific innovation and continuousprocessimprovement by identifying and implementing novel approaches that enhance downstream biologics development workflows
• Partner across multidisciplinary teams, translatingprocessinsights into functional resultsto accelerate the advancement of therapeutic candidates
• Communicate scientific findings with clarity and influence,presentingtechnicalinformationto diverse audiencestosupport project progression and knowledge sharing

Qualifications

• BS orMSinBiochemistry, Biophysics,Biomedical, Chemical Engineering,or a related field, with typically 5-7years (BS) or2-5years (MS) of experience
• Hands-on experienceoperatingAKTAchromatography systemsand Unicornsoftware
• Strong foundation in analyticalcharacterization techniques, includingHPLC,gelelectrophoresis,ELISA,mass spectrometry, and relatedmethods
• Knowledge of biologicsmanufacturingor processdevelopment is a plus
• Solidunderstanding ofprotein structure,molecularattributesand post-translationalmodifications impactingbiologicquality and performance
• Excellent written, verbal, and presentation skills, with the ability to communicate complex scientific concepts to diverse audiences
• Track record of scientific curiosity, innovation, and continuous learning
• Collaborative mindset with a passion for teamwork, scientific rigor, and delivering impactful solutions

Position will be filled at level commensurate with extent of education, experience, and accomplishment— Scientist I or Scientist II

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

This job is eligible toparticipate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.