Scientist: B-Cell Biology

Proclinical Staffing; Palo Alto (CA); On-site; USD 120,000 - 180,000; Full time

Job summary

Proclinical Staffing in Palo Alto, CA, seeks a Scientist specializing in B-Cell Biology to join a dynamic immunology team. The role focuses on supporting preclinical research, designing and executing experiments, analyzing data, and collaborating with cross-functional teams to advance programs.

The ideal candidate holds an advanced degree in immunology, with expertise in B cells or autoimmune disease, hands-on experience in cell culture and molecular assays, and familiarity with RNA-seq data

Qualifications

• PhD in Immunology or related life sciences, or MS with relevant lab experience.
• Expertise in B-cell biology and/or autoimmune disease preferred.
• Experience with primary human/animal tissue handling, cell culture, ELISAs/MSDs, flow cytometry, nucleic acid isolation, and qRT-PCR.
• Familiarity with RNA-seq and/or scRNA-seq data analysis is a plus.
• Strong organizational, problem-solving, and communication skills.
• Proficiency with Microsoft Office and collaboration tools (Zoom, Teams, Box).
• Knowledge of Benchling and GraphPad Prism preferred.

Responsibilities

• Conduct and support translational studies for preclinical programs.
• Perform hands-on in vitro pharmacology experiments and maintain cell cultures and samples.
• Design and oversee in vivo pharmacology studies via CRO partners.
• Manage laboratory reagents, organization, storage, and disposal.
• Collaborate with the lab team to maintain space, equipment, and inventory.
• Record data, prepare technical reports, and summarize findings.
• Communicate project progress to supervisors.
• Develop and implement new assays, execute experiments, and analyze data of moderate complexity.
• Provide guidance and mentorship to staff, researchers or interns.
• Manage timelines to meet project goals and deliverables.
• Present findings at internal meetings and collaborate with cross-functional teams.

Skills

B-cell biology

Autoimmune disease knowledge

In vitro pharmacology

In vivo pharmacology design with CROs

Data analysis (RNA-seq/scRNA-seq)

Organization & problem-solving

Communication skills

MS Office & collaboration tools (Zoom,

Benchling

GraphPad Prism

Education

PhD in Immunology or related life sciences

MS with relevant laboratory experience

Tools

Flow cytometry

qRT-PCR

ELISAs/MSDs

RNA-seq data analysis

Job description

The Scientist - Permanent - Palo Alto, CA

Ready to advance breakthrough immunology research and help shape the future of treatments for infectious and autoimmune diseases?

Proclinical is seeking a Scientist specializing in B-Cell Biology to join a dynamic team in Palo Alto, CA.

Primary Responsibilities:

The successful candidate focuses on supporting preclinical research efforts in immunology and infectious diseases. You will play a key part in designing and executing experiments, analyzing data, and collaborating with cross-functional teams to advance research programs.

Skills & Requirements:

• Advanced degree (PhD) in Immunology or a related life sciences discipline, or an MS with relevant laboratory experience.
• Expertise in B-cell biology and/or autoimmune disease is preferred.
• Proficiency in experimental techniques such as primary human/animal tissue handling, cell culture, ELISAs/MSDs, flow cytometry, nucleic acid isolation, and qRT-PCR.
• Familiarity with RNA-seq and/or scRNA-seq data analysis is a plus.
• Strong organizational, problem-solving, and communication skills.
• Experience with Microsoft Office applications (Word, Excel, PowerPoint) and collaboration tools (Zoom, Microsoft Teams, Box).
• Knowledge of electronic laboratory notebooks (e.g., Benchling) and statistical analysis software (e.g., GraphPad Prism) is preferred.
• Highly organized and precise in laboratory practices and maintenance.

The Scientist's responsibilities will be:

• Conduct and support translational studies for preclinical programs.
• Perform hands-on in vitro pharmacology experiments and maintain cell cultures and biological samples.
• Design and oversee in vivo pharmacology studies conducted through CRO partners.
• Manage laboratory reagents, ensuring proper organization, storage, and disposal.
• Collaborate with the laboratory team to maintain lab space, equipment, and inventory.
• Record experimental data, prepare technical reports, and summarize study findings.
• Communicate project progress effectively to supervisors.
• Develop and implement new assays, execute experiments, and analyze data of moderate complexity.
• Provide guidance, training, and mentorship to technical staff, new researchers, or interns.
• Manage experimental timelines to meet project goals and deliverables.
• Present scientific findings at internal meetings.
• Collaborate with cross-functional teams to support research and program needs.