Scientist 3, Single Cell & Functional Genomics

Genentech; South San Francisco (CA); On-site; USD 103,400 - 192,000; Full time

Benefits offered by this job

Relocation benefits

Job summary

Genentech is seeking a Scientist 3 to execute cutting-edge single-cell and functional genomic techniques to study cancer biology. You'll perform high-throughput screens, deploy single-cell profiling methods, and analyze genomic data to reveal molecular mechanisms and targets for therapy.

The role requires a PhD in a relevant field, hands-on CRISPR screening, and strong data analysis skills in R or Python. Strong collaboration and publication-driven communication are essential.

Qualifications

• PhD in a relevant field such as molecular or cancer biology, genetics or related areas.
• Hands-on experience with single-cell CRISPR screens and data interpretation.
• Strong ability to analyze genomic data using R and/or Python.

Responsibilities

• Execute high-throughput screens in cancer cell lines and models.
• Develop and apply single-cell technologies to profile primary tissues.
• Analyze single-cell perturbation data and broader genomic datasets.
• Collaborate across departments and communicate findings through publications and presentations.
• Lead projects and contribute to new technology opportunities.

Skills

Single-cell CRISPR screens

R

Python

NGS assays

Leadership

Publications

Education

PhD in molecular biology / cancer biology / genetics / immunology / systems biology

Tools

NGS platforms

Job description

The Position

The Department of Cell and Tissue Genomics is seeking a creative, rigorous, and motivated Scientist 3 to execute cutting-edge single-cell and functional genomic techniques to study cancer biology. The successful candidate will perform high-throughput screens, deploy new and existing single-cell profiling methods, and analyze genomic data to enable interrogation of molecular mechanisms underlying disease states and identify candidate targets for therapeutic interventions. Working in collaboration with colleagues in the departments of Research Oncology, Translational Medicine, and/or Computational Sciences, this is a hands-on position with both experimental and computational analysis components.

The Opportunity

• Perform high-throughput screens in cancer cell lines and models
• Develop and apply single-cell technologies to profile primary tissue samples
• Analyze and interpret single-cell perturbation data and broader genomic data
• Effectively collaborate with teams within the department and across the wider organization
• Communicate results clearly through high-impact scientific publications and presentations
• Contribute to identifying new research opportunities and innovative technology applications

Who You Are

• Education: Doctorate degree in a relevant field, including molecular biology, cancer biology, genetics, immunology, systems biology, developmental biology, biochemistry, and/or biomedical engineering
• Screening Experience: Hands-on experience performing and analyzing single-cell CRISPR screens
• Data Analysis: Experience in the analysis of single-cell and genomic data using R and/or Python
• NGS Assay Expertise: Strong foundational background in NGS assays and molecular biology techniques
• Professional Skills: Excellent oral and written presentation skills
• Leadership: Ability to manage multiple projects in parallel, collaborate effectively with multidisciplinary teams, and lead research projects
• Scientific Productivity: Sustained record of productivity in the form of publications and patents

Preferred

• Epigenomics: Experience with epigenomic assays and data analysis
• Disease Expertise: Experience in cancer biology research

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $103,400 - $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This position also qualifies for the benefits detailed below.

Benefits: Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company\'s policy prohibits unlawful discrimination, including but not limited to discrimination on the basis of protected veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form about accommodations for applicants.