Scientist

Spectraforce Technologies, Inc.; Pleasanton (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

Spectraforce Technologies, Inc. in Pleasanton, CA is seeking a Scientist for an onsite, 12-month assignment.

The role focuses on advancing next-generation sequencing (NGS) diagnostics with a strong emphasis on methylation sequencing workflows and collaboration across molecular biology and bioinformatics teams. The candidate will perform cfDNA extraction from plasma, blood, and FFPE tissues, design experiments, analyze data, and maintain detailed documentation to support ongoing R&D efforts in

Qualifications

• Background in molecular biology and human disease studies.
• Experience with NGS library prep and sequencing.
• Excellent written and oral communication.
• Team-oriented with self-motivation.

Responsibilities

• Perform cfDNA extraction from clinical plasma, whole blood, and FFPE tissue.
• Plan and conduct hands-on laboratory experiments under supervision.
• Design, execute and analyze methylation sequencing workflows.
• Analyze data, evaluate results, form conclusions, and plan future experiments.
• Collaborate with molecular biology and bioinformatics groups.
• Operate AXELIOS 1 sequencer in a core lab.
• Keep detailed records of experiments and project information.

Skills

Molecular biology

NGS

Genomics

Bioinformatics

Team collaboration

Communication skills

Tools

AXELIOS 1 sequencer

Job description

Position Title: Scientist

Work Location: 4300 Hacienda Drive, Pleasanton, CA, 94588

Assignment Duration: 12 months

Work Arrangement: Onsite

Position Summary:

Our long term goal is to revolutionize clinical diagnostics through innovation of advanced molecular diagnostic methods facilitating personalized, proactive treatments that lead to improved patient outcomes. This is accomplished first by identifying specific clinical/scientific needs followed by the application of novel molecular technologies to address them. We tackle critical problems standing in the way of the routine clinical use of next generation sequencing (NGS) diagnostics in oncology, genetics, women's health, immunology, and infectious diseases worldwide. We work at the forefront of Research and Early Development to incorporate the latest technology advancements into new sequencing assays and applications. Our high-performance team is looking for new group members who share our drive and have advanced skill sets relevant to NGS, genomics, and bioinformatics. If you would like to work on challenging problems in NGS with the opportunity to invent new diagnostic methods, then this is the place for you.

Background & Context:

Role supports Research and Early Development efforts to advance next-generation sequencing (NGS) diagnostics for oncology, genetics, women's health, immunology, and infectious diseases.

Key Responsibilities:

• Perform cell-free nucleic acids extraction from clinical plasma specimens, whole blood, and formalin-fixed paraffin-embedded (FFPE) tissue
• Work under manager supervision to plan and conduct hands-on laboratory experiments independently
• Design, execute and analyze methods optimizing methylation sequencing workflows
• Analyze data, evaluate results, form conclusions, and determine future experiments
• Collaborate closely with molecular biology and bioinformatics groups to evaluate and identify potential parameters that may impact sequencing performance
• Execute high-throughput sequencing operations on the AXELIOS 1 sequencer within a core laboratory environment
• Keep detailed records of all experiments and project-related information

Qualification & Experience:

• A background in molecular biology and human disease related fields
• Good understanding of NGS library preparation, targeted enrichment, and sequencing
• Ability to work well in teams and across disciplines
• Excellent written and oral communication skills
• The candidate should be passionate and self-motivated with a strong desire to acquire on-the-job training
• Job level (Scientist I/Scientist II) will be determined based on relevant industry experience