Scientist

Aequor; Cambridge (MA); On-site; USD 55,000 - 75,000; Full time

Job summary

Aequor in Cambridge, MA seeks a motivated Bench Scientist II for hands-on protein purification, labeling, and characterization. You will routinely purify recombinant proteins and support downstream analytical and cell culture workflows.

The role involves operating AKTA/FPLC and HPLC systems, working with antibodies and Fab fragments, and collaborating with a team to meet weekly project timelines. This is a fast-paced lab, requiring strong organizational skills and a desire to learn new

Qualifications

• Bachelor’s degree in Biochemistry or a related field.
• At least 1 year of relevant laboratory experience, with 1–2 years of protein purification experience preferred.
• Hands-on experience with recombinant protein purification.
• Experience with AKTA/FPLC and HPLC systems.
• Strong organizational and time-management skills.
• Ability to work effectively in a fast-paced laboratory environment.
• Strong desire to learn and develop new technical skills.
• Ability to work independently as well as collaboratively within a scientific team.

Responsibilities

• Purify multiple recombinant proteins on a weekly basis using established protein purification methods.
• Perform routine protein labeling and final characterization of target proteins, monoclonal antibodies (mAbs), and antibody fragments (Fabs).
• Perform protein labeling using labels including fluorescent dyes, biotin, and other reagents.
• Operate and maintain AKTA/FPLC and HPLC systems for protein purification and analysis.
• Assist with weekly Western blot experiments and related protein characterization activities.
• Support transient and stable mammalian cell culture maintenance, as needed.
• Maintain accurate laboratory records and follow established protocols, safety requirements, and quality standards.
• Manage multiple laboratory activities effectively while meeting weekly project timelines.
• Collaborate with scientists and laboratory team members to troubleshoot experiments and achieve project objectives.
• Demonstrate a strong willingness to learn new techniques and laboratory procedures.

Skills

Protein purification

Mammalian cell culture

Teamwork

Time management

Documentation

Learning agility

Education

Bachelor's degree in Biochemistry or related field

Tools

AKTA/FPLC

HPLC

Job description

Cambridge, MA, United States

Position Summary

We are seeking a motivated Bench Scientist II to support protein purification, protein labeling, characterization, and related laboratory activities. The successful candidate will be responsible for routinely purifying recombinant proteins and supporting downstream analytical and cell culture workflows.

Key Responsibilities

• Purify multiple recombinant proteins on a weekly basis using established protein purification methods.
• Perform routine protein labeling and final characterization of target proteins, monoclonal antibodies (mAbs), and antibody fragments (Fabs).
• Perform protein labeling using a variety of labels, including fluorescent dyes, biotin, and other applicable reagents.
• Operate and maintain familiarity with AKTA/FPLC and Agilent HPLC systems for protein purification and analysis.
• Assist with weekly Western blot experiments and related protein characterization activities.
• Support transient and stable mammalian cell culture maintenance, as needed.
• Maintain accurate laboratory records and follow established protocols, safety requirements, and quality standards.
• Manage multiple laboratory activities effectively while meeting weekly project timelines.
• Collaborate with scientists and laboratory team members to troubleshoot experiments and achieve project objectives.
• Demonstrate a strong willingness to learn new techniques and laboratory procedures.

Required Qualifications

• Bachelor’s degree (BA/BS) in Biochemistry or a related scientific field.
• At least 1 year of relevant laboratory experience, with approximately 1–2 years of protein purification experience preferred.
• Hands-on experience with recombinant protein purification.
• Experience working with AKTA/FPLC and HPLC systems.
• Strong organizational and time-management skills.
• Ability to work effectively in a fast-paced laboratory environment.
• Strong desire to learn and develop new technical skills.
• Ability to work independently as well as collaboratively within a scientific team.

Preferred Qualifications

• Experience with protein labeling techniques.
• Experience working with antibodies, including monoclonal antibodies and/or Fabs.
• Experience with fluorescent and biotin-based protein labeling.
• Experience with Western blotting.Experience maintaining mammalian cell cultures, including transient and stable cell lines.
• Familiarity with protein characterization and analytical techniques.

Core Competencies

• Protein purification and biochemical laboratory techniques
• AKTA/FPLC operation
• HPLC operation and analysis
• Protein and antibody handling
• Experimental organization and documentation
• Time management and prioritizationTroubleshooting and problem-solving
• Teamwork and collaboration
• Willingness to learn

Education

Required: Bachelor’s degree (BA/BS) in Biochemistry or a related field, with at least one year of relevant experience.

Experience Level

1–2 years of relevant protein purification experience

This is a hands-on laboratory position requiring routine execution of protein purification, protein characterization, and related biochemical laboratory procedures. The role may also involve mammalian cell culture and collaboration with multidisciplinary research teams.