Scientific Director, ETCT Innovation

GSK; Upper Providence (Delaware County); On-site; USD 125,000 - 150,000; Full time

Job summary

An established industry player in oncology research is seeking a Scientific Director for Innovation to spearhead the development of cutting-edge antibody drug conjugates (ADCs). This pivotal role involves leading cross-functional teams and collaborating with key business partners to drive innovative therapeutic strategies. The successful candidate will have extensive experience in drug discovery and a proven track record in oncology, making significant contributions to the advancement of targeted biologics. Join a dynamic team dedicated to transforming cancer treatment and enhancing patient outcomes through groundbreaking research and strategic partnerships.

Qualifications

• PhD in life sciences with 5+ years post-doctoral training required.
• Experience in oncology drug discovery and ADC development is essential.

Responsibilities

• Lead initiatives for developing ADCs and partner with internal/external teams.
• Scout for new technologies and build investment proposals for leadership.

Skills

Leadership in drug discovery

Cross-functional team management

Mechanistic testing

Oncology research

Scientific strategy development

Education

PhD in Cancer Biology

Post-doctoral training

Tools

Antibody drug conjugates (ADCs)

Biologics drug discovery

Job description

The Extracellular Targeted Cancer Therapeutics (ETCT) Biology Unit within the Oncology Research Unit is seeking a Scientific Director for Innovation to lead outwardly facing technology and business development initiatives designed to accelerate the build of a targeted biologics portfolio in Oncology. The incumbent will lead cross-functional initiatives to develop the next generation of ADC and interface with key internal/external business partners to accelerate asset development. Additionally, this position will involve consultation with the business development team to assist the identification and assessment of cutting-edge technologies and potential research collaborations. The successful applicant will have prior experience leading matrix teams with oversight of critical path chemistry and biology in the preclinical development of ADC for cancer therapy.

Key Responsibilities:

1. Guide the maturation and de-risking of novel therapeutic concepts, specifically antibody drug conjugates (ADCs), through rigorous mechanistic testing in partnership with internal and external business partners.
2. Talent scout new technology investments and help build proposals for GSK’s senior leadership for investment.
3. Co-lead a team which can collaborate with internal platform groups to deliver success on externally partnered programs and/or technologies.
4. Identify new areas for investment at the preclinical research phase, as well as assist scientific due diligence review of in-licensing clinical opportunities with the business development organization.
5. Prioritize innovation projects and allocate resources effectively to drive successful outcomes.
6. Collaborate with business development teams to establish strategic partnerships and alliances with external organizations, including startups, research institutions, and pharmaceutical companies.

Why you?

Basic Qualifications:

1. PhD in Cancer Biology, Pharmacology, Cellular Biology, or other life science fields with 5+ years post-doctoral training.
2. Experience leading cross-functional drug discovery project teams to develop novel therapeutic platforms for biologics targets.
3. Direct experience developing ADC and novel chemistry.
4. Experience developing and implementing scientific strategies in Oncology.
5. Experience in progressing cancer therapies from target ID to candidate selection and supporting critical path mechanistic biology and/or in vivo translational studies.

Preferred Qualifications:

1. 10+ years pharmaceutical or biotechnology industry research and leadership experience in preclinical oncology biologics drug discovery.
2. Experience establishing scientific relationships in Oncology.
3. Experience working with business development to perform due diligence on oncology assets.
4. Strong peer-reviewed publication, public speaking / presentation and/or inventorship record.
5. The ability to work independently with excellent organizational and interpersonal skills.