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Infosys Limited in Irving, TX seeks an experienced SAP Project Manager to lead brownfield S/4HANA conversions in regulated life sciences environments. You will own end-to-end program delivery across Finance, Supply Chain, Manufacturing, QA, and Commercial, ensuring GxP/CSV and SOX compliance.
The role demands hands-on SAP Activate, cutover management, data migration planning, and cross-functional leadership with global teams to minimize downtime and deliver compliant, timely go-lives.
The Infosys Life Sciences unit is dedicated to advancing the healthcare and pharmaceutical industries through innovative digital solutions. We focus on integrating advanced AI and automation to enhance operational efficiency and support long-term business objectives. Join us to be part of a team that is transforming the life sciences sector, driving innovation, and improving patient outcome.
SAP Project Manager with deep expertise leading brownfield conversions to SAP S/4HANA within regulated, pharma/life sciences environments. This role will own end‑to‑end program delivery across business functions (Finance, Supply Chain, Manufacturing, Quality, Commercial) while ensuring strict compliance with GxP/CSV, SOX, FDA/UDI, and Pharma Quality standards.
In addition, this role includes Cutover Management leadership, responsible for strategy, planning, execution, and governance of all cutover activities across business, IT, data, technical, and manufacturing sites.
The ideal candidate has hands-on delivery of at least one S/4HANA brownfield implementation, strong SAP Activate knowledge, proven system integrator management experience, and extensive execution of cutover cycles, mock conversions, and downtime orchestration in complex global landscapes.
Program & Delivery Management
Lead the end-to-end S/4HANA Brownfield Conversion lifecycle: discovery → planning → build → testing → cutover → hypercare → stabilization.
Own program governance: scope, budget, schedule, RAID, dependencies, KPIs, and executive reporting.
Manage SAP Activate across Discover, Prepare, Explore, Realize, Deploy, Run—including hybrid Agile/Wave-based delivery.
Facilitate cross‑functional governance forums, steering committees, and risk/escalation trajectories.
Brownfield‑Specific Execution
Drive SAP Readiness Check, Simplification Item evaluation, Custom Code Analysis, sizing, and compatibility validation.
Oversee technical conversion with BASIS & infra: SUM/DMO, Maintenance Planner, Stack XML generation, dual maintenance, downtime reduction planning.
Lead custom code remediation, Fiori activation, and Business Partner (BP) conversion.
Define and manage conversion strategy for key data objects: FI docs, open items, materials, batch/serial, BP, etc.
Coordinate multiple mock conversions, dry runs, and system preparation activities.
Cutover Management (Expanded Section for Pharma S/4HANA Brownfield)
Cutover Strategy & Governance
Lead the complete Cutover lifecycle for the S/4HANA brownfield program across all business functions and global sites.
Develop the comprehensive Cutover Strategy, aligned with pharma regulatory, GMP, and validated system requirements.
Establish cutover governance: checkpoints, approvals, command center structure, and communication flow.
Cutover Planning
Build and maintain a detailed Integrated Cutover Plan covering:
Technical conversion activities
Functional steps
Business operations freeze windows
Regulatory and validation checkpoints
MES/WMS/MES/LIMS/PLM and serialization integration tasks
Plan for downtime minimization and coordinate downtime playbooks for manufacturing and distribution environments.
Mock Cutover & Dress Rehearsals
Lead multiple Mock Cutovers, evaluating:
system conversion duration
data readiness
dependencies & integration stability
business process continuity readiness
Identify bottlenecks and drive performance tuning with BASIS, data, and infra teams.
Pharma/Regulated Process Focus
Ensure GxP & CSV-aligned cutover documentation including:
validated procedures for transitions
audit trail controls
change control approvals
batch-impact assessments
Align with 21 CFR Part 11, UDI, ISO 13485, and internal QMS procedures.
Data Migration & Conversion Readiness
Manage data migration workstreams, ensuring:
cleansing
mapping
validation
mock conversion testing
reconciliation & signoffs
Lead cutover-related data validation with QA, manufacturing, supply chain, and finance.
Cutover Command Center Execution
Run the cutover command center during go-live:
Coordinate 24×7 execution teams
Manage issue triage, escalation, and resolution
Ensure adherence to freeze periods and validation controls
Communicate milestone progress to leadership
Go-Live & Hypercare Cutover Support
Ensure deployment readiness and final cutover checklist signoff.
Lead the transition into hypercare including:
stab
At least one end-to-end S/4HANA brownfield conversion delivered in a global environment.
Strong command of SAP Activate, RAID management, budget control, and executive communications.
Experience in life sciences / medical devices / pharmaceuticals with GxP/CSV and SOX compliance.
Proven leadership of system integrators and distributed teams; adept in hybrid Agile execution (Scrum + Stage-Gate).
Familiarity with SUM/DMO, Simplification Items, Fiori, Business Partner conversion, and custom code remediation.
Demonstrated expertise in multi-workstream coordination across core SAP modules (FI/CO, MM, SD, PP, QM; EWM/TM and MDG preferred).
Preferred
PMP, Prince2, PMI-ACP, CSM/SAFe, or SAP Activate Project Manager certification.
Experience with SAP Signavio, Focused Build, SAP Cloud ALM/SolMan, and Tricentis Tosca.
Knowledge of serialization/UDI, labeling, and quality systems in medical devices or pharma.
Background with data migration strategies and tools (e.g., Migration Cockpit, Data Services) and archiving.
Familiarity with security design, GRC, and SoD in regulated environments.
Experience coordinating multi-region go-lives and downtime minimization strategies.
Along with competitive pay, as a full-time Infosys employee you are also eligible for the following benefits:
Infosys is a global leader in next-generation digital services and consulting. We enable clients in more than 50 countries to navigate their digital transformation. With over four decades of experience in managing the systems and workings of global enterprises, we expertly steer our clients through their digital journey. We do it by enabling the enterprise with an AI-powered core that helps prioritize the execution of change. We also empower the business with agile digital at scale to deliver unprecedented levels of performance and customer delight. Our always-on learning agenda drives their continuous improvement through building and transferring digital skills, expertise, and ideas from our innovation ecosystem.
Infosys provides equal employment opportunities to applicants and employees without regard to race; color; sex; gender identity; sexual orientation; religious practices and observances; national origin; pregnancy, childbirth, or related medical conditions; status as a protected veteran or spouse/family member of a protected veteran; or disability.