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University of Minnesota is seeking a Researcher/Lab Manager to advance experiments in DNA repair coordination on meiotic chromosomes. You will use single‑molecule microscopy in live nuclei, high‑resolution imaging, and quantitative analysis while overseeing wet‑lab operations and budgeting.
The role offers mentorship opportunities and collaboration across the lab. The ideal candidate has a strong microscopy background, experience with genome engineering in C.
Summary of Position: The Diezmann lab at the University of Minnesota - Twin Cities is seeking a Researcher/Lab Manager. As a researcher, the candidate will pursue experiments to understand how DNA repair is coordinated along meiotic chromosomes, including single‑molecule microscopy in live nuclei, high‑resolution imaging, quantitative data analysis, and the design and maintenance of transgenic C. elegans strains. As a lab manager, the candidate will oversee wet‑lab operations, microscopy resources, and ordering/budgeting. This position is highly collaborative, with ample opportunities to mentor and learn from lab members, and to publish and present experimental results. The ideal candidate will be excited to help build a lab applying cutting‑edge techniques to uncover new mechanisms in cellular biophysics and chromosome biology.
About our Lab: The Diezmann lab works to understand how biological signals emerge from subcellular molecular dynamics. We use high‑resolution microscopy and genome engineering to study how competing DNA repair pathways are balanced during meiosis to ensure the faithful transmission of genetic material while creating genetic diversity in each generation. Our lab introduced the use of single‑molecule tracking microscopy in live meiotic nuclei in C. elegans, revealing how protein diffusion, binding, and accumulation transduces signals along meiotic chromosomes. Our lab values mutual support, technical mastery, and critical reasoning, and our work supports advances in human reproductive health, crop breeding, and diseases of DNA repair such as cancer.
70% Research Experimentation: Single‑molecule tracking microscopy, high‑resolution imaging, image and statistical data analysis in MATLAB and related pipelines. Design genetic constructs, perform genetic manipulation of C. elegans. Maintain laboratory records, prepare figures, and communicate results.
30% Lab Manager Operations: Administration of ordering and budgeting. Prepare media and other stocks, maintain databases and protocols, safety training and compliance, optimizing lab processes, training new lab members.
All required qualifications must be documented on application materials.
Required qualifications: BA/BS degree in biology, chemistry or related fields plus at least four years of relevant experience, or a combination of education and relevant work experience to equal at least 8 years. At least 4 years of experience with quantitative biological microscopy.
Preferred Qualifications: Master’s degree in biology, chemistry or related fields. Experience in genetics, biochemistry, physical chemistry, and/or cellular biology. Experience with Matlab, R, Python or other high‑level data analysis software. Experience with C. elegans, molecular biology, and/or CRISPR‑Cas9 genome engineering techniques. Demonstrated skills in process and inventory management.
The Department of Genetics, Cell Biology, and Development encompasses a broad range of biological disciplines, including the storage and expression of information, its translation into the workings of individual cells, and the assembly of cells into tissues and organ systems.
Pay Range: $29.00 ($60,320) – $34.00 ($70,720), depending on education/qualifications/experience.
Time Appointment: 100% Appointment.
Position Type: Civil‑Service & Non‑Faculty Labor Represented Staff.
Applications must be submitted online. To be considered for this position, click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.
Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.
To request an accommodation during the application process, please e‑mail employ@umn.edu or call (612) 624‑8647.
The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.
We provide equal access to and opportunity in programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression.
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