Research Technician II- Cheng Lab

Cleveland Clinic; Cleveland (OH); On-site; USD 42,000 - 62,000; Full time

Job summary

Cleveland Clinic Main Campus is seeking a Research Technician II to join the Cheng Lab in the LRI Genomic Medicine Institute. You will participate in daily research activities focused on functional genomics, stem cell disease modeling, and molecular biology, supporting a growing portfolio of funded projects.

Work includes cell culture, sequencing workflows, and general lab operations, with opportunities to contribute to CRISPR-based experiments and NGS library prep while gaining exposure to

Qualifications

• Minimum qualifications: High School Diploma or GED and four years of experience in a research or related laboratory environment
• OR Associate's degree in laboratory science and three years of experience
• OR Bachelor's degree and two years of experience
• OR Master's degree and one year of experience

Responsibilities

• Participate in daily research project activities
• Plan, organize, perform and monitor daily project protocols
• Collect, prepare and maintain required research documentation, including informed consent records, case records, clinical notes and medical reports
• Report and assist with managing protocol deviations, adverse events and other project-related issues
• Be responsible for the general maintenance and upkeep of the lab
• Order and purchase supplies, gather information on new equipment and recommend purchases
• Assist with cell culture, including maintenance of iPSC-derived neurons, microglia, astrocytes, and/or brain organoids
• Support experiments in functional genomics such as CRISPR/Cas9 or CRISPRi/a workflows, Basic molecular biology (PCR, cloning, DNA/RNA extraction) and Next-generation sequencing (NGS) library preparation
• Perform sample processing, reagent preparation, buffer making, and general laboratory organization
• Assist with FACS sample preparation, immunostaining, and microscopy as needed
• Maintain detailed and accurate experimental records in lab notebooks and electronic databases
• Follow standard operating procedures, safety guidelines, and quality control measures

Skills

Cell culture

Molecular biology techniques

Laboratory documentation

Education

Associate's degree in laboratory science

Bachelor's degree with 2+ years experience

Master's degree with 1+ year experience

High School Diploma or GED with 4+ years experience

Tools

FACS

Immunostaining

Microscopy

NGS library preparation

Job description

At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, every day.

We all have the power to help, heal and change lives - beginning with our own. That's the power of the Cleveland Clinic Health System team, and The Power of Every One.

Job Title

Research Technician II- Cheng Lab

Location

Cleveland

Facility

Cleveland Clinic Main Campus

Department

LRI Genomic Medicine Institute-Research Innov and Educ

Job Code

D99981

Shift

Days

Schedule

8:30am-5:00pm

Job Summary

Job Details

Join Cleveland Clinic's Main Campus where research and surgery are advanced, technology is leading-edge, patient care is world class and caregivers are family. Here, you will work alongside a passionate and dedicated team, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world.

As a Research Technologist, you will participate in the design, organization, and execution of daily research activities within the Cleveland Clinic Genome Center, directed by Dr Feixiong Cheng, to support experimental research in functional genomics, stem cell-based disease modeling, and molecular biology. The lab supports a large and growing portfolio of sponsored projects, all of which require sustained, hands-on work in cell culture, sample preparation, sequencing workflows, and overall laboratory operations. Candidates gain exposure to cutting edge functional genomics and disease modeling, contribute to long-term funded projects, and play a meaningful role in discoveries that translate to human health, directly supporting Cleveland Clinic's mission to advance patient care through high-impact biomedical research.

Read more about Dr. Cheng's lab: https://www.lerner.ccf.org/genomic-medicine/cheng/

A caregiver in this role works days from 8:30 a.m. - 5:00 p.m. (flexible start/end times)
Occasional weekend shifts are required.

A caregiver who excels in this role will:

• Participate in daily research project activities.

• Plan, organize, perform and monitor daily project protocols.

• Collect, prepare and maintain required research documentation, including informed consent records, case records, clinical notes and medical reports.

• Report and assist with managing protocol deviations, adverse events and other project-related issues.

• Be responsible for the general maintenance and upkeep of the lab.

• Order and purchase supplies, gather information on new equipment and recommend purchases.

• Assist with cell culture, including maintenance of iPSC-derived neurons, microglia, astrocytes, and/or brain organoids.

• Support experiments in functional genomics such as CRISPR/Cas9 or CRISPRi/a workflows, Basic molecular biology (PCR, cloning, DNA/RNA extraction) and Next-generation sequencing (NGS) library preparation.

• Perform sample processing, reagent preparation, buffer making, and general laboratory organization.

• Assist with FACS sample preparation, immunostaining, and microscopy as needed.

• Maintain detailed and accurate experimental records in lab notebooks and electronic databases.

• Follow standard operating procedures, safety guidelines, and quality control measures.

Minimum qualifications for the ideal future caregiver include:

• High School Diploma or GED and four years of experience in a research or related laboratory environment

• OR Associate's degree in laboratory science and three years of experience

• OR Bachelor's degree and two years of experience

• OR Master's degree and one year of experience

Preferred qualifications for the ideal future caregiver include:

• Bachelor's or Master's degree

• Hands-on experience in cell culture, molecular biology techniques, sample preparation, and laboratory organization

• Comfortable executing routine and semi-technical experiments independently

• Strong time management, documentation skills

• Ability to work in a fast-paced research environment

Physical Requirements:

• Ability to perform work in a stationary position for extended periods

• Ability to operate a computer and other office equipment

• Ability to communicate and exchange accurate information

• Ability to distinguish color
• Manual dexterity to handle specimens and repair equipment
• Ability to lift and transport equipment or specimens weighing up to 20 pounds
• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• Follows standard precautions using personal protective equipment as required.

The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our drug free environment. All offers of employment are followed by testing for controlled substances.

Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption.

Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility.

If applying for a Florida position, please see the following website for more information on the background screening requirements required by the Agency of Health Care Administration: https://info.flclearinghouse.com/

Please review the Equal Employment Opportunity poster.

Cleveland Clinic is pleased to be an equal employment opportunity employer.