Research Technician II - Center for Genomic Medicine - Morini/Alves Labs

Mass General Brigham; Boston (MA); On-site; USD 50,000 - 70,000; Full time

Job summary

Mass General Brigham offers an exciting opportunity for a Research Technician to join their Center for Genomic Medicine. The role entails conducting innovative research in gene editing and pharmacological therapies, with a focus on Familial Dysautonomia. Ideal candidates will have a strong background in neuroscience or human genetics, and will thrive in a collaborative research environment.

Qualifications

• 1-2 years of previous research lab experience required.
• Familiarity with research techniques and methodologies essential.
• Willingness to learn and adapt to new techniques.

Responsibilities

• Conducts efficacy studies using a mouse model of FD.
• Manages mouse colony, including breeding and health monitoring.
• Prepares reports and analyzes data.

Skills

Analytical skills

Data interpretation

Strong computer skills

Education

Bachelor's Degree in a related field

Job description

Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The Morini and Alves Laboratories at the Center for Genomic Medicine, Massachusetts General Hospital (MGH), are seeking a highly motivated Research Technician to support ongoing translational research focused on developing gene editing and pharmacological therapies for Familial Dysautonomia (FD), a rare neurodegenerative disorder.

The successful candidate will play a key role in testing novel gene editing approaches and small-molecule compounds in a mouse model of FD. This includes conducting efficacy studies, genotyping, tissue processing, behavioral assays, and molecular biology techniques such as qPCR, Western blotting, and RNA analysis.

We are looking for a results-driven, team-oriented individual who thrives in a fast-paced and collaborative environment. The ideal candidate is detail-oriented, self-motivated, and comfortable working independently at the bench. A background or strong interest in neuroscience, human genetics, and/or therapeutic development is highly desirable. Prior experience with mouse handling and colony management is strongly preferred.

Qualifications

This position does not require patient care.

Essential Functions

1. Executes protocols of non-routine experiments.
2. Assists PI with determining the most suitable methodology.
3. Performs basic design and modification of protocols.
4. Executes and supports in vivo efficacy studies using a mouse model of FD.
5. Assists in mouse colony management (breeding, genotyping, health monitoring).
6. Calculates, transcribes, and analyzes data.
7. Prepares and presents reports.
8. Organizes and summarizes acquired data using scientific and statistical techniques.
9. Participates in the design of experiments or fieldwork.

Job Description

Education

Bachelor's Degree in a related field of study is required. Can this role accept experience in lieu of a degree? Yes.

Licenses and Credentials Experience

Previous research lab experience 1-2 years required.

Knowledge, Skills, and Abilities

• Analytical skills and ability to resolve technical problems.
• Ability to interpret data results.
• Strong computer skills.
• Demonstrated competence in research techniques and methodologies.

Additional Job Details (if applicable)

Remote Type

Onsite

Work Location

185 Cambridge Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

EEO Statement:

The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.