Research Scientist: Natural Products Synthesis & SAR Expert

University of Mississippi; United States; Vor Ort; USD 90.000 - 130.000; Vollzeit

Zusammenfassung

University of Mississippi seeks a Research Scientist in Chemistry to lead total synthesis and development of reference standards for natural products. The role emphasizes stereochemical elucidation using advanced NMR/MS techniques and SAR studies to improve agrochemical or pharmacological properties of natural products and derivatives.

The position involves publishing results, contributing to patents, and collaborating across disciplines to push forward drug discovery and agrochemical

Qualifikationen

• Ph.D. in Organic Chemistry or closely related discipline.
• Experience isolating, characterizing, and synthesizing natural and synthetic compounds, including post-doctoral work.
• Hands-on mastery of multi-step total syntheses and air- and moisture-sensitive reagents.
• Advanced chromatographic/spectroscopic techniques including GC-MS, LC-MS, and 1D/2D NMR data interpretation.
• Purification methods such as Biotage flash chromatography and column chromatography.

Aufgaben

• Total Synthesis & Reference Standards: Execute complex synthetic routes to access diverse natural products for reference standards or downstream evaluations.
• Stereochemical Elucidation: Determine absolute stereochemistry using 1D/2D NMR and related techniques.
• SAR Studies: Design, synthesize, and evaluate derivatives to optimize agrochemical or pharmacological profiles.
• Scientific Communication: Author peer-reviewed papers, contribute to patent applications, and collaborate across disciplines to advance drug discovery.

Kenntnisse

Total synthesis

Stereochemistry

SAR studies

NMR spectroscopy

Purification methods

Ausbildung

PhD in Chemistry

Tools

ChemDraw

SciFinder

Reaxys

Jobbeschreibung

University of Mississippi seeks a Research Scientist in Chemistry to lead total synthesis and development of reference standards for natural products. The role emphasizes stereochemical elucidation using advanced NMR/MS techniques and SAR studies to improve agrochemical or pharmacological properties of natural products and derivatives.

The position involves publishing results, contributing to patents, and collaborating across disciplines to push forward drug discovery and agrochemical