Natural Products Synthesis Scientist — Total Synthesis & SAR

University-of-Mississippi

Mississippi

On-site

USD 90,000 - 120,000

Full time

9 days ago

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Job summary

The University of Mississippi invites applications for a Research Scientist in Chemistry to lead total synthesis projects and develop reference standards for natural products. The role emphasizes determining absolute stereochemistry and conducting SAR studies to enhance agrochemical or pharmacological properties.

Applicants should have a PhD in a relevant field and strong experience with multi-step syntheses, advanced spectroscopy, and purification techniques.

Qualifications

  • PhD in Organic Chemistry, Medicinal Chemistry, Pharmacognosy, or a closely related discipline.
  • Post-doctoral experience with extensive isolation, characterization, and synthesis of natural and synthetic compounds.
  • Proficiency in modern purification and analytical techniques such as GC-MS, LC-MS and NMR.

Responsibilities

  • Total Syntheses & Reference Standards: Execute complex synthetic routes and total syntheses to access natural products for reference standards and downstream biological evaluations.
  • Stereochemical Elucidation: Apply advanced spectroscopic techniques to determine absolute stereochemistry of complex natural products.
  • SAR Studies: Design, synthesize, and evaluate derivatives to optimize agrochemical or therapeutic profiles.
  • Scientific Communication: Publish in peer-reviewed journals, contribute to patents, and collaborate across disciplines.

Skills

Synthesis expertise
Spectroscopic analysis
SAR design
Scientific communication

Education

PhD in Chemistry or related

Tools

GC-MS
LC-MS
1D/2D NMR
Biotage flash chromatography
Column chromatography
ChemDraw
SciFinder
Reaxys

Job description

The University of Mississippi invites applications for a Research Scientist in Chemistry to lead total synthesis projects and develop reference standards for natural products. The role emphasizes determining absolute stereochemistry and conducting SAR studies to enhance agrochemical or pharmacological properties.

Applicants should have a PhD in a relevant field and strong experience with multi-step syntheses, advanced spectroscopy, and purification techniques.

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