Research Scientist, Lentiviral Vector Purification and Analytics

Novartis; Cambridge (MA); On-site; USD 67,000 - 151,000; Full time

Job summary

Scorpion Therapeutics in Cambridge, MA is seeking a Research Scientist I/II to advance lentiviral vector purification and analytical workflows. You will perform purification steps (clarification, chromatography, TFF) and evaluate quality via molecular- and cell-based assays, while documenting methods and results.

The role requires a BS or MS in bioengineering or virology with 1–3 years of lab purification experience, plus strong communication and collaboration skills.

Qualifications

• BS or MS in bioengineering, virology, or related field (not PhD-level), with relevant lab experience.
• 1–3 years of experience in protein and/or viral vector purification.
• Hands-on chromatography and filtration experience, including TFF and depth filtration.
• Proficiency with Word, Excel, PowerPoint, and GraphPad Prism.
• Excellent oral, written, and interpersonal communication skills.

Responsibilities

• Hands-on execution of lentiviral vector purification activities, including clarification, chromatography, and TFF.
• Execute molecular- and cell-based analytical methods to assess quality of the purified vector.
• Write and review protocols, technical reports, and technology transfer documents with conclusions and recommendations.
• Write and review SOPs, instrument procedures, and other lab documents.
• Plan and prioritize work to meet goals while managing multiple research activities.
• Support experimental design, data analysis, and troubleshooting.
• Identify root causes, implement solutions, and verify effectiveness.
• Present scientific data and contribute openly to discussions.
• Thoroughly document experimental procedures and processes.
• Collaborate across teams, share knowledge, and train team members as needed.

Skills

Coordination

Communication

Collaboration

Learning agility

Self-motivation

Education

BS/MS in bioengineering or virology

Tools

Microsoft Word

Microsoft Excel

Microsoft PowerPoint

GraphPad Prism

Job description

Internal Job Title: Research Scientist I/II

Position Location: Cambridge, MA, onsite

Key Responsibilities:

• Hands-on execution of lentiviral vector purification activities, including clarification, chromatography, and TFF.
• Execute molecular- and cell-based analytical methods to assess quality of the purified vector.
• Write and review protocols, technical reports, and technology transfer documents with conclusions and recommendations.
• Write and review SOPs, instrument procedures, and other lab documents.
• Plan and prioritize work to meet goals while managing multiple research activities.
• Support experimental design, data analysis, and troubleshooting.
• Identify root causes, implement solutions, and verify effectiveness.
• Present scientific data and contribute openly to discussions.
• Thoroughly document experimental procedures and processes.
• Collaborate across teams, share knowledge, and train team members as needed.

Essential Requirements:

• BS or MS in bioengineering, virology, or related field (not PhD-level), with relevant lab experience.
• 1–3 years of experience in protein and/or viral vector purification.
• Hands-on chromatography and filtration experience, including TFF and depth filtration.
• Strong coordination, communication, collaboration, learning agility, and self-motivation.
• Proficiency with Word, Excel, PowerPoint, and GraphPad Prism.
• Excellent oral, written, and interpersonal communication skills.

Desirable Requirements:

• BSL2 experience with AAV, lentiviral, or retroviral vector production.
• Proficiency in aseptic technique, cell culture, molecular biology, and analytical testing.
• Bioreactor experience.

Compensation (expected):

Research Scientist I: $66,800–$124,000; Research Scientist II: $81,200–$150,800. Includes performance-based cash incentive; annual equity may be considered.