Research Scientist II – Neuroblastoma Tumor Immunology (Carbone Lab)

Seattle Children's; Seattle (WA); On-site; USD 68,000 - 102,000; Full time

Job summary

Seattle Children’s is seeking a Research Scientist II to advance our neuroblastoma tumor immunology program. You will design and execute experiments, lead a major project, and contribute to manuscripts and presentations.

The role emphasizes lab leadership, collaboration with team members, and the development of robust experimental methods to drive effective immunotherapies for high-risk neuroblastoma.

Qualifications

• Bachelor’s Degree in engineering or scientific discipline; Master’s degree may be required for certain lab specialties.
• Minimum of two (2) years’ experience in a related area/laboratory setting.
• N/A.

Responsibilities

• Lead design, planning, execution, troubleshooting and analysis of experiments in neuroblastoma immunology.
• Coordinate work across lab members and collaborators; mentor junior researchers.
• Develop rigorous experimental practices and identify operational issues.

Skills

Flow cytometry

Cell culture

Tissue isolation

In vivo techniques

Mouse colony

Data analysis

Education

Bachelor’s Degree in Engineering or Science

Job description

Description: We’re looking for a Research Scientist II to join our team and take a leading role in advancing our research in neuroblastoma tumor immunology. Our lab studies how interactions between NK cells, dendritic cells, and T cells shape anti-tumor immunity, with the goal of understanding how immunotherapies could generate more effective and durable responses in high-risk neuroblastoma.

Job Responsibilities

• 60% Experimental Research: Lead the design, planning, execution, troubleshooting, and analysis of experiments focused on neuroblastoma immunology and cancer immunotherapy.
• 25% Project and Team Leadership: Take primary responsibility for advancing a major research project; coordinate experimental work across lab members and collaborators; provide scientific guidance and mentorship to junior researchers.
• 15% Scientific and Lab Operations: Compose manuscripts and presentations; initiate new research directions; help establish rigorous experimental practices and identify scientific or operational issues that may impede research.

Technical Expertise

• Multiparameter flow cytometry and cell sorting
• Mammalian cell culture and in vitro immunoassays
• Tissue harvest, processing, and immune cell isolation
• Mouse handling and in vivo experimental techniques
• Mouse colony management, including oversight of routine colony operations
• Data analysis related to the above techniques and scientific writing

Required Education And Experience

Bachelor’s Degree in an engineering or scientific discipline; may require a Master’s Degree for certain lab specialties.

Minimum of two (2) years’ experience in a related area/laboratory setting.

Required Credentials

N/A.

Preferred

Additional experience in one or more of the following areas is desirable:

• Advanced microscopy and/or intravital imaging
• Histological and spatial analysis of tissue
• Processing and analysis of human tumor samples
• Computational image analysis using ImageJ/Fiji, Python, or related tools
• Transcriptomic and/or genomic data analysis using R, Python, or related tools
• Preclinical tumor models
• PhD in immunology, cancer immunology, immunotherapy, pediatric cancer, or a related field.

Compensation Range

$32.87 - $49.31 per hour

Salary Information

This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.

Disclaimer for Out of State Applicants

This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors.

Benefits Information

Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website www.seattlechildrens.org/careers/benefits.

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

Our founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families’ ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country.

U.S. News & World Report consistently ranks Seattle Children’s among the nation’s best children’s hospitals. For more than a decade, Seattle Children’s has been nationally recognized in key specialty areas. We are honored to be one of the nation’s very best places to care for children and the top-ranked pediatric hospital in Washington and the Pacific Northwest.

As a Magnet designated institution, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it’s delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.

Our Commitment

Seattle Children’s welcomes people of all experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our patients and families. Our organization recruits, employs, trains, compensates, and promotes based on merit without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves.

Seattle Children’s is proud to be an Equal Opportunity Workplace and affirmative Action Employer.