Research Lab Technician I

Brigham and Women's Hospital, Inc.; Boston (MA); On-site; USD 60,174,000 - 83,126,000; Full time

Job summary

Mass General Brigham invites applicants for a full-time Research Assistant in the Department of Pathology. The role focuses on developing ultrasensitive protein detection technologies, including Simoa and MOSAIC, for biomarker discovery in human biofluids and diagnostic applications.

You will perform experiments, optimize assay performance, analyze data, and document results, with collaboration across the Harvard Medical School and Wyss Institute environments.

Qualifications

• Sound analytical and organizational skills.
• High degree of computer literacy.
• Requires good oral and written communication skills.
• Ability to structure tasks and set priorities.
• Ability to troubleshoot solutions.
• Document, analyze, and interpret experimental data.
• Work independently and collaboratively in a multidisciplinary research environment.
• Strong attention to detail and accuracy in lab procedures.

Responsibilities

• Independently performs routine and non-routine experiments of moderate to high complexity.
• prepares reagents and evaluates antibodies for assays.
• Develops and optimizes Simoa and MOSAIC assays.
• Generates calibration curves and performs biomarker measurements in human biofluids.
• Analyzes data using statistical techniques and reports results.
• Collaborates with PI and team, coordinates tests and schedules.
• Documents experimental work accurately and in detail.
• Assists in training new staff and ordering lab supplies.

Skills

Analytical skills

Computer literacy

Oral and written communication

Attention to detail

Independent and collaborative work

Education

BA/BS in biological, chemical, physical or related science

Job description

Site: The Brigham and Women's Hospital, Inc.Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.Job SummaryUnder general supervision of the Principal Investigator and in accordance with established hospital policies and procedures, provides technical support for research involving the development and application of ultrasensitive biomarker detection technologies. Performs laboratory experiments, documents experimental results, and analyzes data using appropriate statistical methods.A position is open for a full-time Research Assistant in the Department of Pathology at Brigham and Women’s Hospital. The laboratory develops and applies ultrasensitive protein detection technologies, including single molecule array (Simoa) and Molecular On-bead Signal Amplification for Individual Counting (MOSAIC), for biomarker detection and diagnostic applications. The candidate will develop, optimize, and perform ultrasensitive single- and multiplex protein assays to measure low-abundance biomarkers in human biofluids. Specific applications may include cancer biomarker detection and validation, early disease detection, treatment-response monitoring, and other diagnostic applications.The candidate will work independently, under general supervision, to perform experiments, optimize assay performance, analyze data, and measure biomarkers that may be undetectable using conventional methods. Research conducted by the candidate in collaboration with the research team will contribute to the development of new diagnostic technologies and address underlying biological questions.The position will also provide opportunities to interact and collaborate within the broader Harvard Medical School and Wyss Institute for Biologically Inspired Engineering research environments.1. Independently performs routine and non-routine experiments of moderate to high complexity. Experimental work may include preparing reagents, conjugating and evaluating antibodies and other binding reagents, developing and optimizing Simoa and MOSAIC assays, generating calibration curves, performing single- and multiplex biomarker measurements in human biofluids, evaluating assay performance, and troubleshooting experimental procedures.2. Calculates, transcribes, and analyzes data using moderate to advanced statistical techniques.3. Performs literature searches, prepares presentations and progress reports, and assists in preparing manuscripts for publication. Corresponds and communicates progress professionally with collaborators and scientific community.4. In collaboration with PI or Research Manager, establishes new and modifies existing research techniques.5. Coordinates schedule of tests and procedures. Documents experimental work accurately and in detail.6. Coordinates lab activities such as bio-safety trainings.7. Assists in the orientation and training of new staff.8. Ordering and inventory of laboratory supplies.QualificationsEducationBA/BS in biological, chemical, physical, or related science required. Prior laboratory research experience preferred but not essential.Can this role accept experience in lieu of a degree?YesExperiencePrior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferredKnowledge, Skills and Abilities• Sound analytical and organizational skills• High degree of computer literacy.• Requires good oral and written communication skills• Ability to logically and effectively structure tasks and set priorities• Ability to identify potential problems and trouble-shoot solutions.• Ability to accurately document, analyze, and interpret experimental data.• Ability to work both independently and collaboratively in a multidisciplinary research environment.• Strong attention to detail and ability to perform quantitative laboratory procedures accurately.Additional Job Details (if applicable)Remote TypeOnsiteWork Location60 Fenwood RoadScheduled Weekly Hours40Employee TypeRegularWork ShiftDay (United States of America)Pay Range$21.00 - $29.01/HourlyGrade5At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.EEO Statement:2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.Mass General Brigham Competency FrameworkAt Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.