RESEARCH ASSOCIATE/STUDENT

Roskamp Institute; Sarasota (FL); On-site; USD 35,000 - 48,000; Full time

Job summary

Roskamp Institute in Sarasota, FL, seeks a Research Associate/Student for a full-time role within its Neuroscience Ph.D. program.

The position focuses on translational research in Alzheimer's disease, with hands-on training from day one and involvement in cutting-edge lab and clinical research projects. Ideal candidates will hold a Master’s degree in a scientific field or a Bachelor’s with demonstrated laboratory experience, and be eager to contribute to mechanistic studies using rodent and

Qualifications

• Master's degree in a scientific field, or a Bachelor's degree with demonstrated scientific laboratory experience.
• Experience with cell culture and basic laboratory techniques.
• Interest in neuroscience research and translational studies.

Responsibilities

• Support translational research efforts investigating cerebrovascular decline and Alzheimer's disease.
• Perform cellular culture, tissue analysis, and basic experimental assays as part of the project.
• Assist in generation and analysis of data from rodent and human cell-based models.

Skills

Laboratory experience

Education

Master's degree in a scientific field

Bachelor's degree with demonstrated laboratory experience

Job description

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RESEARCH ASSOCIATE/STUDENT

Full Time Sarasota, FL, US

5 days ago Requisition ID: 1015

Join an exciting, multidisciplinary PhD program that offers hands-on training from day one, bridging cutting-edge laboratory science with clinical research. We are seeking motivated and dedicated doctoral students for the Neuroscience Ph.D. program at the Roskamp Institute, which currently has openings for a 4-year Ph.D. project in Alzheimer's disease (AD) research.

Roskamp Institute projects are all focused on translational research, with analysis of clinical samples to define the conditions under investigation, and extensive characterization of relevant preclinical models in order to identify and develop diagnostic strategies and therapeutic targets.

This PhD student will join our translational team investigating the mechanisms by which genetic and metabolic factors influence cerebrovascular decline and late-onset Alzheimer's disease (LOAD). Our research integrates cross-scale validation using pharmacologic and genetic interventions in novel LOAD mouse models, complemented by our cutting-edge 3D humanized cell-based microfluidic Brain-Chip platform.

Techniques associated with this Roskamp Ph.D. project include:

• Culturing and analysis of cellular and microfluidic brain-chip samples


• Tissue-specific isolation, culturing, and analysis of rodent samples


• Mutagenic and environmental risk factors on a humanized mouse platform of LOAD


• Antibody-based analytical approaches - immunoblotting, ELISA, and MSD assays


• Activity assays - metabolic measurements, oxidative stress, and antioxidant defenses


• Rodent manipulation including glymphatic, cerebrovascular, and behavioral studies


• Blood brain barrier analysis - permeability, leukocyte adhesion, waste elimination


• Cerebrovascular analysis - capillary stalling, hypoperfusion, blood flow, and reactivity


• Neuropathological and angioarchitectural analyses - microscopy, immunohistochemistry

The Roskamp Institute is a leader in the field of neuroscience, with a strong reputation for developing novel therapies for conditions such as traumatic brain injury (TBI), Alzheimer's disease and Gulf War Illness. The Institute's cutting-edge research environment offers unmatched opportunities for multidisciplinary training and hands-on experience, working with experts in translational neuroscience. Sarasota, Florida, is known for its beautiful, pristine beaches and pleasant weather year-round, making it an ideal place to live and work. As part of the Roskamp Institute, you will not only advance your career but also enjoy the benefits of living in a vibrant coastal community.

Qualifications Required

• Master's degree in a scientific field, or a Bachelor's degree with demonstrated scientific laboratory experience.