Research Associate (Single Cell Transcriptomics)

Neurona Therapeutics; South San Francisco (CA); On-site; USD 90,000 - 120,000; Full time

Job summary

Neurona Therapeutics in South San Francisco, CA is seeking a Research Associate specializing in single cell transcriptomics to join our growing team. You will design and execute experiments, prepare samples for NGS, and work with multidisciplinary colleagues to advance transformative neuroscience research.

A BS or MS in biology and hands-on experience with single cell NGS workflows and cell sorting are required.

Qualifications

• BS or MS in Biology or related field.
• Experience with single cell NGS sample prep workflow.
• Experience with flow cytometry and cell sorting (FACS/MACS).
• Molecular biology techniques: PCR, qPCR, DNA/RNA extraction.
• Strong organizational and analytical skills.
• Detail-oriented and able to work in a fast-paced start-up.

Responsibilities

• Design and execute single cell RNA seq experiments from prep to QC.
• Prepare samples for sequencing and other applications.
• Perform cell sorting (FACS/MACS) experiments.
• Improve workflows and streamline processes.
• Manage sample inventory and records.
• Maintain detailed experimental documentation.
• Manage reagents and equipment calibration.
• Collaborate with multidisciplinary teams.
• Analyze data and present results.
• Support related discovery projects.

Skills

Single cell NGS

Flow cytometry

Molecular biology

Data analysis

Attention to detail

Team work

Communication

Education

BS or MS in Biology

Tools

cDNA library prep

Microfluidics

FACS

Job description

We are hiring! Our ideal candidates are self-motivated individuals who have clearly demonstrated a passion for scientific research. This is a fantastic opportunity to join a small team, work on transformative science, and build an exciting, science-driven company. Neurona is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

Position:Research Associate (Single Cell Transcriptomics)

Location: South San Francisco, CA

Job Id:360

# of Openings:1

Research Associate (Single Cell Transcriptomics)

Responsibilities

• Design, plan and execute experiments using single cell RNA sequencing pipeline from sample preparation and capture to NGS sequencing library preparation and QC with high precision
• Prepare single cell and single nuclei samples for next-generation sequencing (NGS) and other applications
• Conduct fluorescence and/or magnetic-activated cell sorting experiments
• Help optimize and improve workflow, and streamline processes
• Collect, organize, and manage sample inventory
• Organize and maintain detailed experimental records in accordance with industry standards
• Manage reagent inventory and equipment calibration/maintenance
• Collaborate with multidisciplinary teams and colleagues
• Analyze data, interpret and present results at team meetings
• Support other Discovery projects involving human neuronal cell culture and cell-based assays

Required Qualifications

• BS or MS degree in Biology, Molecular/Cell Biology or related field
• Experience with single cell NGS sample prep workflow (cell capture using microfluidics, cDNA and library preparation, QC and sequencing)
• Experience with flow cytometry and fluorescence activated and/or magnetic cell sorting (FACS/MACS)
• Familiarity with DNA/RNA library QC techniques (Tapestation, Bioanalyzer, Qubit, etc.)
• Working knowledge of standard molecular biology techniques (PCR, qPCR, gel electrophoresis, DNA/RNA extraction)
• Strong organizational and analytical skills
• Willingness to perform repetitive tasks with high accuracy and superb attention to detail
• Willingness to learn and expand skill set and contribute to emerging needs in a highly dynamic start-up environment
• Ability to multitask while working within fast-paced timelines
• High integrity, excellent written, verbal and interpersonal communication skills
• Strong team player and problem-solver, able to work on teams and independently

Preferred Qualifications

• 2+ years of relevant hands on laboratory experience in academia or industry
• Familiarity with single-cell RNA sequencing data analysis
• Familiarity with histochemical techniques and basic microscopy
• Experience with sterile human stem cell and neuronal cell culture
• Basic knowledge of stem cell biology and neurodevelopmental biology

We are open to hiring at various experience levels. The final job title and compensation will be determined by the candidate’s qualifications and experience.

This job description is not intended to be exhaustive and may evolve as business needs change. Duties, responsibilities, and activities may be modified or assigned at any time with or without notice.

Neurona Therapeutics
490 Forbes Blvd, Suite 600
South San Francisco, CA 94080
[e-mail]