Research Associate Position - Lazar laboratory

University of Pennsylvania Perelman School of Medicine; Philadelphia (Philadelphia County); Sur place; USD 65 000 - 90 000; Plein temps

Résumé du poste

The Division of Endocrinology, Diabetes and Metabolism at the University of Pennsylvania Perelman School of Medicine invites applications for a Research Associate. This position focuses on thyroid hormone receptor mechanisms in liver and other tissues, using cutting-edge genomic approaches.

The successful candidate will work with ChIP-seq, single-cell RNA-seq, ATAC-seq and mutant mouse models; opportunity to develop a tailored training plan and advance a career in academia.

Qualifications

• Ph.D. required for the role.
• Minimum of three years of postdoctoral research experience.
• Experience with animal models of hypothyroidism and hyperthyroidism.
• Proficiency with molecular biology techniques including ChIP-seq, single-cell RNA-seq, ATAC-seq, and generation of mutant mice models.

Responsabilités

• Conduct experiments to elucidate mechanisms of thyroid hormone receptor function in liver and other tissues.
• Develop novel methods for gene transcription analysis.
• Collaborate with lab members and contribute to project goals.
• Be involved in the longer-term goals related to diabetes and metabolic liver disease.

Connaissances

Molecular biology

ChIP-seq

Single-cell RNA-seq

ATAC-seq

Mutant mouse models

Animal thyroid models

Formation

Ph.D. degree

Description du poste

University of Pennsylvania: Perelman School of Medicine: Perelman School of Medicine - Department of Medicine: Perelman School of Medicine - Medicine - Endocrinology, Diabetes and Metabolism

Location

Philadelphia, PA

Open Date

Apr 27, 2026

Deadline

Apr 27, 2028 at 11:59 PM Eastern Time

Description

The Division of Endocrinology, Diabetes and Metabolism in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Applicants must have a Ph.D. degree. Position requires a minimum of three years of postdoctoral research experience.

Responsibilities may include experiments related to determining mechanisms underlying the functions of thyroid hormone receptors in cells and in vivo by developing novel methods of gene transcription and analysis in liver and other tissues. Applicant must have experience working with animal models of hypothyroidism and hyperthyroidism, and expertise in molecular biology techniques including ChIP-seq, single cell RNA-seq, ATAC-seq, and generation of mutant mice models. The longer-term goal is understanding mechanisms relating to diabetes, obesity, and their comorbidities including metabolic liver disease.

The successful applicant will have an opportunity to develop a customized training experience in research that allows the individual to attain personal career objectives while developing a career in an academic setting.

The Research Associate will be expected to collaborate with other members of the lab in their research areas and give their contributions.