Research Associate Position in Kidney Genetics and Genomics

University of Pennsylvania Perelman School of Medicine; Philadelphia (Philadelphia County); On-site; USD 60,000 - 90,000; Full time

Job summary

The Division of Renal-Electrolyte and Hypertension within the Department of Medicine at the University of Pennsylvania seeks a Research Associate for its Academic Support Staff. This role centers on human genetics and genomics applied to kidney disease and offers opportunities to advance multi-omic approaches.

The successful candidate will lead research projects, perform functional studies, mentor technicians and students, and collaborate with investigators across Penn Medicine. A Ph.D.

Qualifications

• Ph.D. required in a relevant biomedical field.
• Experience applying genetic and genomic approaches to human disease.
• Experience with exome/genome sequencing and interpretation of variants.

Responsibilities

• Lead research projects on rare genetic variants predisposing to kidney diseases.
• Conduct functional studies in cellular and vertebrate models; use sequencing technologies.
• Analyze and interpret complex genomic data and mentor staff and students.
• Present findings at national and international meetings and publish in peer-reviewed journals.

Skills

Human genetics

Genomics

Genetic epidemiology

Molecular genetics

Research leadership

Education

Ph.D. degree

Tools

DNA microarrays

Exome sequencing

Genome sequencing

Mouse models

Transcriptomics

Job description

University of Pennsylvania: Perelman School of Medicine - Department of Medicine - Renal-Electrolyte and Hypertension

Location

Philadelphia, PA

Open Date

Aug 14, 2026

Deadline

Aug 14, 2028 at 11:59 PM Eastern Time

Description

The Division of Renal-Electrolyte and Hypertension in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of human genetics, genomics, genetic epidemiology, molecular genetics, or a closely related biomedical research field, with demonstrated research experience applying genetic and genomic approaches to human disease. Experience in kidney genetics and rare kidney disease research is preferred, including research involving nephrotic syndrome, focal segmental glomerulosclerosis, congenital kidney and urinary tract abnormalities, or related disorders. Experience with exome and/or genome sequencing, analysis and interpretation of genetic variants, and functional characterization of disease-associated variants is also preferred. Applicants must have a Ph.D. degree.

Responsibilities may include leading research projects directed toward the discovery and characterization of rare genetic variants predisposing to rare kidney diseases, including congenital anomalies of the kidney and urinary tract, ADAMTS13-related diseases, and nephrotic syndrome. Responsibilities will include conducting functional studies in cellular and vertebrate disease models; utilizing DNA microarrays, exome and genome sequencing technologies, mouse models, and transcriptomic, epigenomic, and proteomic approaches; analyzing and interpreting complex genomic and molecular data; providing scientific leadership for research projects; supervising laboratory technicians, junior bioinformaticians, and students; presenting research findings at national and international scientific meetings; and publishing results in peer-reviewed scientific journals.

The successful applicant will have an opportunity to advance their expertise in kidney genetics, genomics, and rare kidney disease research within a highly collaborative academic research environment. The successful applicant will have opportunities to lead multidisciplinary research projects, expand expertise in genomic and multi-omic approaches, conduct functional studies of disease-associated genetic variants, mentor junior research staff and trainees, collaborate with investigators across Penn Medicine, and disseminate findings through peer-reviewed publications and presentations at national and international scientific meetings.

The successful candidate will join the Division of Renal-Electrolyte and Hypertension in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania and participate in a collaborative research program focused on understanding the genetic and molecular mechanisms underlying rare kidney diseases.