Research Associate Position in Kidney Genetics and Genomics

University of Pennsylvania; Philadelphia (Philadelphia County); On-site; USD 70,000 - 100,000; Full time

Job summary

University of Pennsylvania invites applications for a Research Associate in Kidney Genetics and Genomics. The role focuses on discovery and characterization of rare genetic variants related to kidney diseases, with opportunities to lead multidisciplinary projects and publish findings.

The successful candidate will perform functional studies, analyze multi-omics data, supervise lab personnel, and collaborate with Penn Medicine investigators in a highly collaborative environment.

Qualifications

• Expertise in human genetics/genomics or related biomedical field.
• Experience applying genetic/genomic approaches to human disease.
• Experience with sequencing data (exome/genome) and variant interpretation.

Responsibilities

• Lead research projects on rare kidney diseases and genetic variants.
• Perform functional studies using cellular and vertebrate models.
• Analyze complex genomic data and present findings at meetings.
• Mentor junior staff and students and contribute to publications.

Skills

Genomics

Molecular genetics

Data analysis

Education

Ph.D. degree

Job description

Research Associate Position in Kidney Genetics and Genomics

Location:

Philadelphia, PA

Open Date:

Aug 14, 2026

Close Date:

Aug 14, 2028

The Division of Renal-Electrolyte and Hypertension in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of human genetics, genomics, genetic epidemiology, molecular genetics, or a closely related biomedical research field, with demonstrated research experience applying genetic and genomic approaches to human disease. Experience in kidney genetics and rare kidney disease research is preferred, including research involving nephrotic syndrome, focal segmental glomerulosclerosis, congenital kidney and urinary tract abnormalities, or related disorders. Experience with exome and/or genome sequencing, analysis and interpretation of genetic variants, and functional characterization of disease-associated variants is also preferred. Applicants must have a Ph.D. degree.

Responsibilities may include leading research projects directed toward the discovery and characterization of rare genetic variants predisposing to rare kidney diseases, including congenital anomalies of the kidney and urinary tract, ADAMTS13-related diseases, and nephrotic syndrome. Responsibilities will include conducting functional studies in cellular and vertebrate disease models; utilizing DNA microarrays, exome and genome sequencing technologies, mouse models, and transcriptomic, epigenomic, and proteomic approaches; analyzing and interpreting complex genomic and molecular data; providing scientific leadership for research projects; supervising laboratory technicians, junior bioinformaticians, and students; presenting research findings at national and international scientific meetings; and publishing results in peer-reviewed scientific journals.

The successful applicant will have an opportunity to advance their expertise in kidney genetics, genomics, and rare kidney disease research within a highly collaborative academic research environment. The successful applicant will have opportunities to lead multidisciplinary research projects, expand expertise in genomic and multi-omic approaches, conduct functional studies of disease-associated genetic variants, mentor junior research staff and trainees, collaborate with investigators across Penn Medicine, and disseminate findings through peer-reviewed publications and presentations at national and international scientific meetings.

The successful candidate will join the Division of Renal-Electrolyte and Hypertension in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania and participate in a collaborative research program focused on understanding the genetic and molecular mechanisms underlying rare kidney diseases.

Equal Employment Opportunity Statement:

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.