Research Associate Position in Kidney Genetics and Genomics

University of Pennsylvania Perelman School of Medicine; Philadelphia (Philadelphia County); Presencial; USD 65.000 - 95.000; Jornada completa

Descripción de la vacante

The University of Pennsylvania Perelman School of Medicine seeks a Research Associate in the Division of Renal-Electrolyte and Hypertension. This full-time role focuses on discovery and characterization of rare kidney diseases through genetic and genomic approaches.

Applicants must hold a Ph.D. and have expertise in human genetics, genomics, and related areas, with opportunities to mentor staff and disseminate findings at major conferences.

Formación

• Ph.D. required with demonstrated research in human genetics or related fields.
• Experience applying genetic/genomic approaches to human disease.
• Kidney genetics or nephrology research experience preferred.

Responsabilidades

• Lead research projects on rare kidney diseases and genetic variants.
• Perform functional studies in cellular and vertebrate models.
• Analyze genomic and multi-omic data and interpret results.
• Supervise staff and trainees.
• Present findings at meetings and publish in journals.

Conocimientos

Human genetics

Genomics

Molecular genetics

Genetic epidemiology

Exome sequencing

Genome sequencing

Educación

Ph.D. degree

Herramientas

DNA microarrays

Exome sequencing

Genome sequencing

Mouse models

Transcriptomics

Proteomics

Descripción del empleo

University of Pennsylvania: Perelman School of Medicine: Perelman School of Medicine - Department of Medicine: Perelman School of Medicine - Medicine - Renal-Electrolyte and Hypertension

Location

Philadelphia, PA

Open Date

Aug 14, 2026

Deadline

Aug 14, 2028 at 11:59 PM Eastern Time

Description

The Division of Renal-Electrolyte and Hypertension in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of human genetics, genomics, genetic epidemiology, molecular genetics, or a closely related biomedical research field, with demonstrated research experience applying genetic and genomic approaches to human disease. Experience in kidney genetics and rare kidney disease research is preferred, including research involving nephrotic syndrome, focal segmental glomerulosclerosis, congenital kidney and urinary tract abnormalities, or related disorders. Experience with exome and/or genome sequencing, analysis and interpretation of genetic variants, and functional characterization of disease-associated variants is also preferred. Applicants must have a Ph.D. degree.
Responsibilities may include leading research projects directed toward the discovery and characterization of rare genetic variants predisposing to rare kidney diseases, including congenital anomalies of the kidney and urinary tract, ADAMTS13-related diseases, and nephrotic syndrome. Responsibilities will include conducting functional studies in cellular and vertebrate disease models; utilizing DNA microarrays, exome and genome sequencing technologies, mouse models, and transcriptomic, epigenomic, and proteomic approaches; analyzing and interpreting complex genomic and molecular data; providing scientific leadership for research projects; supervising laboratory technicians, junior bioinformaticians, and students; presenting research findings at national and international scientific meetings; and publishing results in peer-reviewed scientific journals.
The successful applicant will have an opportunity to advance their expertise in kidney genetics, genomics, and rare kidney disease research within a highly collaborative academic research environment. The successful applicant will have opportunities to lead multidisciplinary research projects, expand expertise in genomic and multi-omic approaches, conduct functional studies of disease-associated genetic variants, mentor junior research staff and trainees, collaborate with investigators across Penn Medicine, and disseminate findings through peer-reviewed publications and presentations at national and international scientific meetings.
The successful candidate will join the Division of Renal-Electrolyte and Hypertension in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania and participate in a collaborative research program focused on understanding the genetic and molecular mechanisms underlying rare kidney diseases.