Research Associate - Physiology & Cell Biology

The-Ohio-State-University-Wexner-Medical-Center; Columbus (OH); On-site; USD 60,000 - 80,000; Full time

Job summary

The Ohio State University Wexner Medical Center seeks a Research Associate to contribute to planning, design, execution, and management of research projects in mitochondrial biology and cardiac cell research. Responsibilities include mitochondrial isolation, functional assays, measurements of mitochondrial redox state, ROS production, and oxidative stress, and advanced microscopy analyses.

The role involves data analysis, developing methodologies, coordinating lab activities, and assisting the

Qualifications

• Bachelor's Degree required; 3 years of relevant experience with an Associate's Degree, or 1 year with a Bachelor's Degree.
• Ability to translate, adapt and apply knowledge in biological/health science research.
• Experience in a biological/health science research capacity is preferred.

Responsibilities

• Plan, design, execute, and manage research projects in mitochondrial biology and cardiac cell research.
• Isolate mitochondria and perform functional assays.
• Measure mitochondrial redox state, ROS production, and oxidative stress.
• Contribute to manuscript preparation, reports, and presentations for conferences; assist in grant proposals.
• Coordinate laboratory activities and oversee routine maintenance of equipment.

Skills

Mitochondrial isolation

Functional assays

Mito redox state

ROS measurement

Oxidative stress

Fluorescence microscopy

Electron microscopy analysis

Education

Bachelor's degree or equivalent education/experience

Job description

The Department of Physiology and Cell Biology seeks a Research Associate to contribute to the planning, design, execution, and management of research projects in a foundational biological/health science laboratory investigating mitochondrial function and dysfunction, cardiac cell biology, and mechanisms of cardiac disease. Responsibilities include mitochondrial isolation, functional assays, measurements of mitochondrial redox state, reactive oxygen species (ROS) production and oxidative stress, mitochondrial electrophysiology, fluorescence and holographic microscopy, and electron microscopy image analysis. The laboratory experiments and performs advanced molecular, cellular, or other specialized techniques. Experience with mitochondrial isolation, functional assays, and measurements of mitochondrial redox state, ROS production, and oxidative stress is highly desirable. Experience with fluorescence microscopy and electron microscopy image analysis is preferred. Clinical training or a background in medicine, particularly with an interest in cardiovascular disease and mitochondrial pathophysiology, is preferred. Responsibilities include collecting, analyzing, and interpreting research data; assisting in the development and refinement of methodologies, experimental designs, sampling techniques, and analytical approaches; and establishing appropriate controls, criteria, and research standards. The Research Associate critically reviews relevant scientific literature, supports the preparation of manuscripts, reports, and presentations for national and international conferences, and contributes to project documentation. The role also assists the principal investigator in preparing grant proposals to secure new or renewal extramural funding. Additional duties include coordinating laboratory activities and work assignments for lab personnel; overseeing routine maintenance and testing of laboratory equipment; and performing other tasks as assigned to advance the research mission.

Minimum Education Required

Bachelor’s Level Degree or equivalent combination of education and experience.

Required Qualifications

Bachelor's Degree or equivalent experience required; 3 years of relevant experience required with Associate's Degree, or 1 years of relevant experience required with Bachelor's Degree. Ability to translate, adapt and apply academic and/or practical knowledge in the conduct of biological/health science research is required. Experience in a biological/health science research capacity is preferred.

Function: Research and Scholarship

Sub Function: Research

Career Band: S

Career Level: S1

Thank you for your interest in working at Ohio State.

The university is an equal opportunity employer, including veterans and disability.

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.