Research Associate, Molecular & Cellular Immunology

Stylus Medicine, Inc.; Cambridge (MA); Presencial; USD 85.000 - 95.000; Jornada completa

Descripción de la vacante

Stylus Medicine, Inc. is seeking a motivated Research Associate for the Molecular and Cellular Immunology team in Cambridge, MA. You will assist in generating nucleic acid materials and conducting in vitro cell experiments to advance non-viral, recombinase-based genetic medicines.

You’ll collaborate with engineers and biologists to move transformational therapies forward. The role emphasizes hands-on cloning, nucleic acid work, data analysis, and meticulous record-keeping in a fast-paced,

Formación

• Hands-on molecular biology experience including PCR, cloning, transformations, and plasmid prep.
• Experience with mammalian cell culture, tumor cell lines, T cells or PBMCs.
• Familiarity with LNPs and CAR-T cells preferred; strong data interpretation skills.
• Demonstrated ability to troubleshoot experiments and document results meticulously.
• Excellent written and verbal communication; collaborative and fast-paced environment.

Responsabilidades

• Perform in vitro T cell experiments to evaluate recombinase-based engineering strategies.
• Clone and prepare nucleic acid materials and/or LNPs to support cell culture work.
• Analyze data and create reports to guide project direction.
• Communicate findings clearly to cross-functional teams.
• Maintain detailed lab records and inventory in compliance with data integrity standards.

Conocimientos

Mammalian cell culture

Flow cytometry

Data interpretation

Scientific communication

Team collaboration

Educación

Bachelor’s degree in Biology or related field

Herramientas

PCR

Cloning

Bacterial transformations

Minipreps

Maxipreps

In vitro transcription

LNP preparation

CAR-T cell handling

Descripción del empleo

About Stylus Medicine:

StylusMedicine is developing transformativein vivo genetic medicines to unlock cures.Styluscombines engineered recombinases with non-viral delivery to specifically encode therapeutics. The company’s approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond.

About the Role:

Stylus Medicine is seeking a highly motivated and collaborative Research Associate to join the Molecular and Cellular Immunology team. In this role, the Research Associate will assist in generating nucleic acid materials and performing in vitro cell experiments, supporting the advancement of genetic medicines that leverage engineered recombinases delivered through non-viral methods. Working closely with cross-functional teams, this is a unique opportunity to work on the front lines of innovation and contribute to the advancement of transformational therapies.

Key Responsibilities & Accountabilities:

• Perform in vitro T cell experiments to evaluate efficiency of recombinase-based engineering strategies and characterize the functional ability of resulting CAR-T cells
• Perform cloning and prepare nucleic acid and/or LNPs to support cell culture experiments
• Analyze and interpret data and produce data reports to inform project direction
• Effectively communicate findings to internal teams
• Maintain detailed and accurate laboratory records in compliance with data integrity and documentation standards

Qualifications & Skills:

• Bachelor’s degree in Biology, Bioengineering, Immunology, or a related field
• Hands-on molecular biology experience, including PCR, cloning, bacterial transformations, minipreps, maxipreps, and in vitro transcription
• Hands-on mammalian cell culture expertise, including culturing tumor cell lines and primary T cells/PBMCs, co-culture experiments, flow cytometry, and genomic DNA extraction
• Familiarity producing targeted LNPs and/or working with CAR-T cells is preferred
• Demonstrated ability to execute, interpret, and troubleshoot experiments, both independently and collaboratively
• Experience maintaining meticulous records, including documenting and maintaining an organized lab notebook, lab inventory, and experimental results
• Excellent communication skills, with a team-first mindset and the ability to convey technical information
• Highly collaborative working style and ability to adapt in a fast paced, rapidly developing environment
• Enthusiasm and curiosity to learn and apply new lab techniques across a variety of sub-disciplines

Pay Range: $85,000-$95,000