Research Associate in Human Immunology - Laura Su's lab

University of Pennsylvania; United States; On-site; USD 65,000 - 90,000; Full time

Job summary

University of Pennsylvania is seeking a Research Associate in Human Immunology to join Laura Su's lab in the Division of Rheumatology. Based in Philadelphia, this role focuses on T cell biology, multi-omics data analysis, and translational immunology research.

The successful candidate will independently drive projects, mentor junior members, and contribute to publications on immune dysregulation and potential biomarkers for autoimmune diseases. A Ph.D. is required for this position.

Qualifications

• Ph.D. in immunology or related field.
• Deep expertise in T cell biology and bioinformatics.
• Experience with bulk and single-cell sequencing data.
• Proficiency in R or Python and statistical modeling.

Responsibilities

• Perform T cell stimulation, antibody staining, and cell sorting.
• Prepare bulk and single-cell sequencing libraries.
• Analyze and integrate RNA-seq, ATAC-seq, TCR-seq, and BCR-seq data using R or Python.
• Apply advanced statistical modeling and communicate results clearly.

Skills

T cell biology

Bioinformatics

Tissue culture

Flow cytometry

RNA-seq analysis

TCR-seq

BCR-seq

R or Python

Statistics

Collaborative skills

Education

Ph.D. degree

Tools

R

Python

Job description

Research Associate in Human Immunology - Laura Su's lab

Location: Philadelphia, PA

Open Date: Jul 09, 2025

Deadline: Jul 09, 2027 at 11:59 PM Eastern Time

The Division of Rheumatology in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of T cell biology and bioinformatics. The ideal candidate will bring deep expertise in tissue culture and flow cytometry, and a broad range of immunologic techniques. A proven track record in analyzing bulk and single-cell RNA-seq, TCR-seq, and BCR-seq data is essential. Candidates must be proficient in advanced statistical and computational methods and have a solid understanding of adaptive immunity. We are looking for a highly self-motivated individual with strong problem-solving skills, effective communication, and excellent organizational abilities. The candidate must be able to work independently and collaboratively. Applicants must have a Ph.D. degree.

Responsibilities may include performing T cell stimulation, antibody staining, cell sorting, preparing bulk and single-cell sequencing libraries, analyzing and integrating RNA-seq, ATAC-seq, TCR-seq, and BCR-seq multi-omic datasets using R or Python. Experience with advanced statistical modeling is expected. Familiarity with spatial transcriptomics is a plus.

The successful applicant will have an opportunity to contribute to publication-driven projects aimed at understanding immune dysregulation in autoimmune diseases and identifying novel biomarkers for type 1 diabetes (T1D). This position offers significant independence, leadership opportunities on high-impact projects, mentorship of junior lab members, and active involvement in cutting-edge translational immunology research. The role includes strong support for authorship and professional development to foster research independence within a highly collaborative and intellectually stimulating environment.

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.