Research Associate III, Biomarker

Crown Bioscience; San Diego (CA); On-site; USD 60,000 - 65,000; Full time

Job summary

Crown Bioscience, a JSR Life Sciences company, is seeking a Research Associate to support biomarker studies and help meet quality standards in oncology programs.

Responsibilities include histology, IHC, spatial transcriptomics, and related assays; document procedures, analyze data, and report findings while collaborating with the global biomarker team.

Qualifications

• Bachelor's degree in biotechnology, cell biology, immunology, oncology, or related discipline.
• Hands-on histology experience (1+ year) with slide-based lab work.
• At least three years of combined experience in immunohistochemistry or pathology.
• Ability to operate routine histological procedures (tissue grossing, embedding, sectioning, staining, IHC/IF).
• Proficiency with MS Office and familiarity with statistical analysis tools.

Responsibilities

• Carry out histology, pathology, immunohistochemistry, spatial transcriptomic, and fluorescent slide assays.
• Conduct flow cytometry and additional assays (proteomics, hematology, NGS) as needed.
• Follow SOPs and training sessions to ensure quality and consistency.
• Record experimental procedures and data, and submit timely reports to supervisors.
• Analyze, summarize, and report experimental data to supervisors.
• Communicate effectively within the global biomarker team and with other departments.
• Participate in day-to-day management of the laboratory team.
• Manage biomarker lab facilities according to experiment needs and quality systems.
• Fulfill other tasks assigned by leaders.

Skills

Histology

Immunohistochemistry

Flow cytometry

Data analysis

Education

Bachelor's degree in biotechnology or related field

Tools

MS Office

Statistical analysis software

Job description

Crown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) dedicated to advancing human health by partnering with biotech and pharmaceutical companies that are at the forefront of drug discovery and development in oncology and immuno-oncology.

Providing a range of integrated solutions, including preclinical research services, translational platforms, and clinical trial support. Its offer includes the world's largest commercially available patient-derived xenograft (PDX) collection and more than 600 tumor organoid models utilizing Hubrecht Organoid Technology, covering 22 cancer indications.

Crown Bioscience's expertise extends across a diverse portfolio of platforms and services that utilize in vivo, in vitro, ex vivo, and in silico methods, along with advanced laboratory services that span the entire drug development timeline. Additionally, it maintains an extensive biobank of liquid and human biospecimens, complete with clinical histories.

Operating from 11 facilities in the US, Europe, and APAC—including laboratories accredited by the College of American Pathologists (CAP) and the International Organization for Standardization (ISO)—Crown Bioscience upholds the highest standards of quality and reliability in its research environments.

Summary

The purpose of the Research Associate position is to provide support on biomarker studies to meet the company's goals, objectives and quality standards.

Responsibilities

• Responsible for a variety of histology, pathology, immunohistochemistry, spatial transcriptomic, and fluorescent slide assays.
• Other duties may include a variety of experiments such as flow cytometry, pathology/IHC, proteomics, hematology, NGS
• Carry out work in strict accordance to SOPs and training sessions.
• Carefully record the experimental process and data and submit timely reports to supervisors.
• Analyze, summarize, and report experimental data and relevant documents to supervisors.
• Effective communication within the global biomarker team and with other departments.
• Participate in the support and daily management of the laboratory team.
• Manage biomarker lab facilities according to experiment needs and quality systems.
• Be able to fulfill other tasks assigned by leaders.
• B.S. or above in biotechnology, cell biology, immunology, oncology or other related disciplines.
• Hands on experience (minimum 1 year) with histology and slide-based lab work
• Able to operate routine histological procedure such as tissue grossing, samples embedding, sectioning, chemical staining, IHC, IF, etc.
• Knowledge of basic histological principles, especially related to oncology.
• Proficient in using MS Office software and familiar with statistical analysis and the application of related analysis software.
• At least three years of combined experience in a field related to immunohistochemistry or pathology.

Preferred Requirements

• Good communication skills and a positive attitude.
• Lab supervisory or management experience (stocking, validation, quality assurance, etc.)
• Eager to learn new and advanced techniques.

The California salary range for this position is: $60,000-$65,000

Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.