Research Associate II, Production

BigHat; San Mateo (CA); On-site; USD 75,000 - 88,000; Full time

Benefits offered by this job

Bonus

Stock options

Benefits

Job summary

BigHat Biosciences in San Mateo, CA is seeking a Research Associate I, Production to drive automated antibody production and high-throughput data generation on our platform. You will contribute to scaling operations and ensure rigorous documentation of experiments.

Ideal candidates have a STEM background, hands-on lab experience with molecular biology, and comfort working on a startup team with shifting schedules and cross-functional collaboration.

Qualifications

• BS in Biology or Chemistry with 1+ year of industry experience.
• Experience in process execution, lab method development and troubleshooting.
• Ability and willingness to work specific day schedules (e.g., 7AM-3PM or 10AM-6PM).
• Hands-on with automated liquid handlers; LIMS experience is a plus.
• Experience with molecular biology techniques.
• Efficient time management and ability to handle multiple projects.
• Strong record-keeping and communication skills.
• Nice-to-haves: barcode systems and Google Workspace tools.

Responsibilities

• Perform automated and manual high-throughput processing on the BigHat platform.
• Contribute to scaling up platform and production-grade data generation.
• Support PRAS functions with reagent manufacturing efforts.
• Execute experiments to optimize platform performance.
• Keep detailed records using documentation tools and communicate results.
• Collaborate on SOPs for sample processing.
• Work with team to implement process improvements in production workflows.
• Operate automated liquid handlers and analytical instruments.

Skills

Automated liquid handling

Molecular biology

Data analysis

Lab documentation

Team communication

Time management

Education

BS in Biology or Chemistry

Tools

Hamilton

OpenTrons

Tecan

Agilent systems

LIMS

Job description

Research Associate I, Production

Department: Lab Science

Employment Type: Full Time

Location: San Mateo, CA

Description

The role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate I, Production role to power our high-throughput, automated platform for antibody production and deep molecular characterization.

*At BigHat we believe in titles that are commensurate with skill set, relative organizational impact, and value contribution; more or less experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.

Key Responsibilities

• Perform automated and manual high-throughput processing on the BigHat platform, including DNA preparation, protein expression, and protein characterization.
• Contribute to the scaling up of BigHat’s platform and production-grade data generation.
• Support BigHat’s Platform Reagents & Assay Support (PRAS) function by contributing to in-house reagent manufacturing efforts.
• Execute experiments to optimize the performance efficiency of BigHat’s platform.
• Keep a detailed record of all experiments using BigHat’s documentation tools, and clearly communicate results and challenges.
• Collaborate on the creation of laboratory standard operating procedures (SOPs) for sample processing.
• Collaborate closely with BigHat team members to identify, design, and implement critical process and operational improvements to production workflows and laboratory systems.
• Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.

Skills Knowledge and Expertise

• BS in Biology or Chemistry, with 1+ year(s) of industry experience
• Experience in process execution, laboratory method development, optimization, and troubleshooting.
• Ability and willingness to work specific workday schedules as needed, for example 7AM to 3PM or 10AM to 6PM.
• Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, OpenTrons, Tecan, Agilent systems). Experience with LIMS is a nice-to-have.
• Experience with molecular biology techniques and general lab practices.
• Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
• Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
• Excellent record-keeping abilities to document experimental work and analytical data.
• Nice-to-haves include previous experience working with barcoding systems, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.)

Total Rewards

The salary estimated for this position is $75,000 - $88,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.