Research Associate II New MBC Lab

BridgeBio Inc.; San Carlos (CA); On-site; USD 135,000 - 147,000; Full time

Benefits offered by this job

Market-leading compensation

401(k) with employer match

Employee Stock Purchase Program (ESPP)

Hybrid work model

Paid holidays & PTO

Job summary

BridgeBio Inc. in California is seeking a Research Associate to execute, analyze, and report results for biological assays in a preclinical program.

The role focuses on enzyme activity measurements, assay development, and data interpretation within a GLP-compliant environment. The candidate will contribute to safety, regulatory readiness, and collaboration across teams, with strong emphasis on hands-on laboratory work and meticulous documentation.

Qualifications

• Education requirement: Bachelor’s or Master’s in Biochemistry, Genetics, Molecular Biology or Pharmacology.
• Experience with enzyme assays and GLP environments.
• Familiarity with immunoassays and biochemical assays.
• Proficiency in Western blotting and SDS-PAGE.
• Ability to work with tissues for in vitro assays.
• Strong attention to detail and independence with teamwork.

Responsibilities

• Laboratory operations related to enzyme activity and inhibition. Planning and execution of experiments to measure inhibitory activity of small molecule drug candidates against target proteolytic enzymes.
• Adhere to company standards, and compliance in current industry standards and practices
• Adhere to safety regulations for handling and disposing of human plasma/serum and reagents
• Proper maintenance of laboratory notebooks and forms in accordance with company policies and practices. Routine maintenance, and upkeep of laboratory

Skills

Enzyme assays

GLP experience

Immunoassay

Biochemical assay

Western Blotting

SDS-PAGE

In vitro tissue assays

Attention to detail

Team collaboration

Education

Biochemistry

Genetics

Molecular Biology

Pharmacology

Job description

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allowsscience and small teams of experts to lead the way. We build bridges to groundbreaking advancements in raredisease, anddevelop life-changing medicines for patients with unmet needs as fast as humanly possible. Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we’llask"why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.

What You’ll Do

The Research Associate will execute, analyze, and report results for biological assays for preclinical program.

Responsibilities

• Laboratory operations related to enzyme activity and inhibition. Planning and execution of experiments to measure inhibitory activity of small molecule drug candidates against target proteolytic enzymes
• Adhere to company standards, and compliance in current industry standards and practices
• Adhere to safety regulations for handling and disposing of human plasma/serum and reagents
• Proper maintenance of laboratory notebooks and forms in accordance with company policies and practices. Routine maintenance, and upkeep of laboratory

Where You’ll Work

This is not a remote work position.

Who You Are

• Education requirement
• Bachelor’s or Master’s degree in Biochemistry, Genetics, Molecular Biology or Pharmacology
• Enzyme assays
• 4-5 years in Pharmaceutical Diagnostic in R&D or GLP environment
• Knowledge of GLP practice desired
• Skills Immunoassay and biochemical assay
• Laboratory experience with Western Blotting and SDS-PAGE is preferred. Basic knowledge of immunoassays and fluorescence biochemistry. Hands on experience in protease assays in plate format with colorimetric or fluorometric detection is desired. Ability to work with tissues for in vitro assays
• Strongly self-motivated individual with attention to detail
• Good interpersonal skills, flexibility and works well independently and within a team environment

Travel

Travel not required except physical laboratory presence during work week.

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

$135,000 - $147,000 USD

As a global company, our comprehensive benefits may vary based on location. We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.

For BridgeBio Full-Time U.S Based Roles:

• Market-leading compensation
• 401(k) with employer match
• Employee Stock Purchase Program (ESPP)
• Pre-tax commuter benefits (transit and parking)
• Referral bonus for hired candidates
• Subsidized lunch and parking on in-office days
• 100% employer-paid medical, dental, and vision premiums for you and your dependents
• HealthSavings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
• Fertility & family-forming benefits
• Expanded mental health support (therapy and coaching resources)
• Hybrid work model with flexibility
• Flexible, “take-what-you-need” paid time off and company-paid holidays
• Comprehensive paid medical and parental leave to care for yourself and your family

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
• We provide career pathing through regular feedback, continuouseducationand professional development programs via LinkedIn Learning,LifeLabs, &BetterUpCoaching
• We celebratestrong performancewith financial rewards, peer-to-peer recognition, and growth opportunities