Research Associate I - Theodoris Lab

Gladstone Institutes; San Francisco (CA); On-site; USD 59,000 - 68,000; Full time

Benefits offered by this job

People -work with talented teammates

Meaningful place to grow and learn

Healthy work-life balance

Competitive salary

Excellent benefits

Job summary

Gladstone Institutes in San Francisco seeks a Research Associate I with a background in experimental genomics to join the Theodoris Lab within the Cardiovascular Disease and Data Science institutes.

You will perform molecular biology and genomics experiments, culture iPSCs, and contribute to single-cell and ChIP-seq studies while collaborating with computational biologists.

This role includes lab operations, safety, mentorship of junior members, and presenting findings in lab meetings.

Qualifications

• BS/BA in molecular biology, genomics, bioengineering, or related field.
• 1+ year of related laboratory experience.
• Proficiency in tissue culture, including iPSCs.
• Experience with RNA/DNA purification, PCR, and cloning.
• Experience in experimental genomics, including sequencing library prep (e.g., single-cell sequencing, ChIP-seq).
• Strong organizational skills and ability to work independently and collaboratively.

Responsibilities

• Perform molecular biology and genomics experiments, including RNA/DNA purification, PCR, cloning, and sequencing library preparation.
• Conduct cell culture experiments, particularly with iPSCs.
• Contribute to single-cell and/or ChIP-seq experiments and analyses.
• Manage laboratory operations, including organization, ordering supplies, and maintaining safety compliance.
• Collaborate closely with computational biologists to integrate experimental and analytical approaches.
• Actively participate in lab meetings, present findings, and contribute to research discussions.
• Assist in the training and mentorship of junior lab members.

Skills

Molecular biology

Genomics

iPSC culture

PCR

Cloning

Nucleic acid prep

Sequencing prep

Single-cell sequencing

ChIP-seq

Lab operations

Collaboration with computational biol.

Mentorship

Education

BS/BA in related field

Job description

Description:

The laboratory of Christina Theodoris, MD, PhD, is seeking a talented and motivated Research Associate I with a background in experimental genomics to join the research program in the Gladstone Institute of Cardiovascular Disease and the Gladstone Institute of Data Science and Biotechnology.

The Theodoris Lab focuses on leveraging cutting-edge experimental genomics and machine learning to map the gene networks driving cardiovascular disease and to develop network-correcting therapies. This is a unique opportunity to work at the interface of experimental and computational biology in a highly collaborative and interdisciplinary environment.

What you will do:

• Perform a variety of molecular biology and genomics experiments, including RNA/DNA purification, PCR, cloning, and sequencing library preparation.
• Conduct cell culture experiments, particularly with induced pluripotent stem cells (iPSCs).
• Contribute to single-cell and/or ChIP-seq experiments and analyses.
• Manage laboratory operations, including organization, ordering supplies, and maintaining compliance with safety protocols.
• Collaborate closely with computational biologists to integrate experimental and analytical approaches.
• Actively participate in lab meetings, present findings, and contribute to research discussions.
• Assist in the training and mentorship of junior lab members.

What you will need:

• BS/BA in a related field (e.g., molecular biology, genomics, bioengineering, or a similar discipline).
• 1+ years of related laboratory experience.
• Proficiency in tissue culture, especially with induced pluripotent stem cells (iPSCs).
• Hands‑on experience with molecular biology techniques such as RNA/DNA purification, PCR, and cloning.
• Experience in experimental genomics, including sequencing library preparation (e.g., single‑cell sequencing, ChIP-seq).
• Strong organizational skills, attention to detail, and the ability to work both independently and collaboratively.

What is preferred:

• Prior experience in cardiovascular biology, stem cell differentiation, or gene regulation studies.
• Familiarity with bioinformatics tools or experience collaborating with computational researchers.
• A demonstrated track record of scientific initiative, including contributions to publications or research presentations.

Salary Range

$28.35/hr. ($58,971) - $32.67/hr. ($67,949)

Gladstone Perks & Benefits

• People -work with talented, committed, and supportive teammates within an organization that values each member of its community.
• A meaningful place to grow and learn -whether it’s your professional skills or scientific knowledge, we have the resources and environment to advance either so you can better support Gladstone's mission to drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and excellent environment.
• Healthy work/life balance -you are highly engaged and productive at work because you can have time to recharge and enjoy a vibrant life outside of work.
• Compensation -competitive salary. Title and salary will be commensurate with education and experience.
• Excellent benefits -generous medical, dental, vision, retirement plan, paid vacation, commuter benefits, access to free shuttle transportation.

Gladstone is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, sex, religion, national origin, ancestry, age, marital status, medical condition, physical or mental disability, veteran status, sexual orientation, or any other non‑job related characteristic. We make all employment decisions so as to further this principle of equal employment.