Research Associate I, Pharmaceutical Development ~ Contract

Initial Therapeutics, Inc.; Brisbane (CA); On-site; USD 114,616,000 - 157,597,000; Part time

Job summary

Nurix Therapeutics, Inc. is seeking a Research Associate I, Pharmaceutical Development to provide scientific, technical, and hands-on support of drug discovery and product development from early discovery to clinical trial enabling studies.

You will prepare and characterize preclinical formulations, perform stability testing with HPLC/UPLC, and assist with oral solid dosage form development. Strong lab skills, documentation, and experience with potent compounds are required; 2–4 years of

Qualifications

• BS/BA or higher in chemistry, pharmaceutics, engineering, or related field with 2-4 years of industry experience.

Responsibilities

• Prepare and characterize preclinical formulations in support of multiple programs.
• Perform stability and solubility testing using HPLC/UPLC.
• Assist with pre-formulation and formulation development for oral solid dosage forms.
• Contribute to internal and external presentations and publications.

Skills

HPLC/UPLC

Mass Spec

Documentation

Microsoft 365

Safe handling of potent compounds

Weighing & Pipetting

Education

BS/BA in chemistry or related field

Tools

XRD

Job description

Research Associate I, Pharmaceutical Development ~ Contract

Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development, and

commercialization of small molecule therapies designed to modulate cellular protein levels as a novel

treatment approach for cancer and immune disorders. Leveraging Nurix's extensive expertise in E3

ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated

discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of

enzymes that can modulate proteins within the cell. Nurix's drug discovery approach is to either harness

or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively

decrease or increase cellular protein levels.

Description

Nurix is looking for a Research Associate I, Pharmaceutical Development to provide scientific, technical,

and hands-on support of drug discovery and product development related to small molecules from early

discovery to clinical trial enabling studies.

• Prepare and characterize preclinical formulations in support of multiple programs.
• Perform stability and solubility testing using HPLC/UPLC.
• Assist with pre-formulation and formulation development for oral solid dosage forms.
• Contribute to internal and external presentations and publications.

Qualifications

• Thorough understanding of basic chemistry principles
• Excellent basic quantitative laboratory skills including weighing, pipetting, and use of volumetric

glassware

• Strong basic HPLC/UPLC skills and understanding (XRD and Mass Spec experience a plus)
• Excellent organizational and documentation skills
• Proficiency in Microsoft 365
• Experience in safe handling of potent compounds
• BS/BA or higher in chemistry, pharmaceutics, engineering, or related field with 2 - 4 years of industry experience

Salary Range: 40/hr - 55/hr

Location: Brisbane, CA - Onsite