Research Associate I, Molecular Biology/Biochemistry

Watchmaker Genomics; Boulder (CO); On-site; USD 65,000 - 80,000; Full time

Benefits offered by this job

Performance bonus

Equity

Flexible time off

Job summary

Watchmaker Genomics in Boulder, Colorado, is hiring a Research Associate I to join the R&D team. Based onsite, you will execute established molecular biology protocols, document results, and contribute to the development of proprietary reagents for genomics applications under senior scientists.

The role offers hands-on training in NGS, enzyme biochemistry, and product workflows, with opportunities for growth within a dynamic biotech environment and a pathway toward impact in research and

Qualifications

• BS in molecular biology, biochemistry, or a related discipline.
• Experience with core molecular biology techniques and sequencing workflows preferred.
• Strong documentation and data-tracking skills required.

Responsibilities

• Execute molecular biology experiments, including PCR, qPCR, and NGS sample prep.
• Document procedures, observations, and results in lab notebooks and systems.
• Perform routine bioinformatic analyses under senior scientists.
• Contribute to launch of enzymes and genomics products.
• Participate in team meetings and scientific discussions.
• Identify observations that support process improvements.

Skills

Molecular biology techniques

PCR

qPCR

NGS

Data analysis

Documentation

Team collaboration

Bioinformatics

Education

BS in molecular biology/biochemistry or related discipline

Tools

DNA/RNA enzymes knowledge

PCR instruments

Sequencing workflows

Job description

Position Type: Full-Time Employee

Department: Research & Development, Applications

Location: Boulder, CO (onsite)

Experience: BS in molecular biology, biochemistry, or a related discipline + 0 years of experience

Watchmaker Genomics is a global life science company based in Boulder, Colorado with an R&D and Production facility in Cape Town, South Africa. Our team is passionate about innovation and values collaboration, creativity, and scientific rigor.

We believe that the intersection of biology, engineering, and computer science presents exciting opportunities for developing novel technologies that promote research and improve human health. Watchmaker Genomics specializes in the design, development, and production of DNA- and RNA-modifying enzymes that enable high-growth applications in genomics, molecular diagnostics, and personalized medicine.

Position Summary

Watchmaker is inviting applications for the full-time position of Research Associate I, based in Boulder, Colorado.

This position reports to a Research Scientist II and will contribute to a research program focused on the development and characterization of novel, proprietary reagents for genomics applications. The Research Associate I will execute established experimental protocols, maintain accurate laboratory records, and participate as an active member of the R&D team under the guidance of senior scientists.

This role is well suited for someone eager to develop hands-on laboratory skills in a dynamic, fast-paced biotech environment. The successful candidate will gain valuable exposure to next-generation sequencing technologies, enzyme biochemistry, and commercial product workflows, with opportunities to grow as they build their scientific foundation.

Responsibilities

• Execute molecular biology experiments, including PCR, qPCR, buffer optimization and next-generation sequencing sample preparation workflows
• Accurately document all experimental procedures, observations, and results in laboratory notebooks and data management systems
• Perform routine bioinformatic analyses using established pipelines under the direction of senior scientists
• Contribute to a team responsible for launch of commercially successful enzymes and genomics products
• Participate in team meetings and contribute to group scientific discussions
• Identify and communicate observations that may support process improvement

Skills and Requirements

The candidate should hold a BS in molecular biology, biochemistry, or a related discipline. Experience in the following areas is highly desirable: next-generation sequencing (NGS), DNA sample preparation, PCR, qPCR and NGS data analysis. Knowledge of DNA- and RNA-modifying enzymes is a plus.

The following skills and experience are requirements for the position:

• Hands-on experience with molecular biology techniques
• Ability to follow written protocols precisely and communicate deviations clearly to supervisors
• Self-motivation and sound personal task management skills
• Careful attention to detail and commitment to accurate experimental documentation
• Strong interpersonal skills and an ability to work as an effective team member
• Familiarity with basic data analysis tools (spreadsheets, descriptive statistics)
• Experience with standard molecular biology techniques such as PCR, qPCR, vector design, and gene cloning methods
• Excellent organizational skills and outstanding attention to detail
• Good communication and personal task management skills and a high level of self-motivation

Education

• BS in Molecular biology, biochemistry, or a related discipline

Compensation

The base compensation for the Research Associate I role starts at $65,000 - $80,000 + bonus + equity; actual pay will be adjusted based on skills and experience. Employees are eligible for Flexible Time Off, Holidays, employer covers 75% of base medical plan with buy-up options, EAP (employee assistance program), employer paid dental, employer paid vision, employer paid $25,000 life/AD&D policy, paid parental leave, and a 401(k) retirement plan with a 4% match.

Application Requirements

To apply for the position, please submit the following in a PDF format on watchmakergenomics.com:

• Letter of motivation (upload where it says cover letter)
• Resume or Curriculum vitae, highlighting relevant qualifications and experience

Applications without a Letter of Motivation will not be considered. Local candidates preferred.

Applications will be accepted on a rolling basis and the position will remain open until filled; however, early submission is encouraged as review will begin immediately.

If selected to participate in the interview process, the names and contact information of three professional references who are able to assess your suitability for the position in terms of the specified requirements will be requested.

Watchmaker Genomics is committed to being an equal opportunity employer and creating a culturally diverse environment. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability status, age, or veteran status or any other characteristics as protected by applicable law.

All applicants will be asked if currently eligible to work in the United States of America; and if now or in the future will require visa sponsorship to continue working in the United States.

This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable federal, state, and local laws.