Research Associate I/II, Bioprocess Development

Flagship Pioneering, Inc.; Cambridge (MA); Vor Ort; USD 65.000 - 94.000; Vollzeit

Benefits dieser Stelle

Healthcare coverage

Annual incentive program

Retirement benefits

A broad range of other benefits

Zusammenfassung

Flagship Pioneering in Cambridge, MA, seeks a Research Associate I/II to help build and optimize a microbial fermentation platform for recombinant protein production. You will support bench-scale workflows, run batch and fed-batch experiments, and work under the Senior Scientist I, Bioprocess Development.

The ideal candidate is hands-on, meticulous, and able to operate independently in a fast-paced startup.

Qualifikationen

• Hands-on experience in microbial fermentation, microbiology, or bioprocess development.
• Experience operating bench-scale bioreactors with aseptic technique.
• Strong organizational and documentation skills.
• Ability to independently run experiments and troubleshoot processes.

Aufgaben

• Operate, monitor, and troubleshoot shake flask and bench-scale fermentation systems for batch and fed-batch experiments.
• Prepare media, inoculum, and feed solutions for fermentation runs.
• Set up, sterilize, calibrate, and maintain fermentation reactors.
• Perform routine analytical work, including OD measurements and metabolite analysis.
• Contribute to safe, rigorous laboratory operations.
• Collaborate with strain engineering, downstream, and analytical teams to scale process development.

Kenntnisse

Microbial fermentation

Aseptic technique

Bioprocess development

Bench-scale bioreactors

Documentation

Troubleshooting

Tools

HPLC

Fermentation data analysis tools

Jobbeschreibung

Flagship Pioneering is a platform innovation company that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health, sustainability and beyond exponentially accelerate scientific progress in areas ranging from disease detection and treatment and nature-positive agriculture to novel applications of AI that are driving the creation of new technologies.

What sets Flagship apart is our ability to advance science and technology by uniting innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

The Role

We are seeking a highly motivated Research Associate I/II to support the development and optimization of microbial fermentation processes for recombinant protein production. We're looking for someone who is excited to help build and scale a fermentation platform from the ground up. Reporting to the Senior Scientist I, Bioprocess Development, this individual will play a key role in executing and scaling microbial fermentation workflows in a fast‑paced startup environment.

The ideal candidate is highly hands‑on, technically rigorous, and comfortable operating independently in a dynamic research setting. This role requires strong practical experience with bench‑scale bioreactors, microbial culture techniques, fermentation analytics, and laboratory operations.

• Operate, monitor, and troubleshoot shake flask and bench‑scale microbial fermentation systems, executing batch and fed‑batch experiments in support of process development objectives.
• Prepare media, inoculum, and feed solutions for fermentation runs.
• Set up, sterilize, calibrate, and maintain fermentation reactors.
• Perform routine analytical work, including OD measurements and metabolite analysis.
• Contribute to safe, rigorous laboratory operations.
• Collaborate closely with strain engineering, downstream, and analytical teams to support integrated process development as the platform scales.

Professional Experience & Qualifications

• Hands‑on experience in microbial fermentation, microbiology, bioprocess development, or related laboratory environments
• Experience in operating and maintaining bench‑scale bioreactors for microbial fermentation workflows, with strong understanding of aseptic technique and microbial culture handling
• Strong organizational and documentation skills
• Ability to independently execute experiments and troubleshoot routine process issues

Preferred Experience

• Experience with fed‑batch fermentation processes
• Familiarity with HPLC‑based analysis of sugars, organic acids, or fermentation metabolites
• Experience with recombinant protein expression systems
• Experience supporting process optimization or scale‑up activities
• Familiarity with fermentation data analysis and process monitoring tools

Location

Cambridge, MA

About Flagship Pioneering

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID‑19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com. At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer

All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

The salary range for this role is $65,000 - $93,500.

Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience.

• Healthcare coverage
• Annual incentive program
• Retirement benefits
• A broad range of other benefits

Compensation and benefits information is based on FL112's good faith estimate as of the date of publication and may be modified in the future.

When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI‑assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of your personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [e-mail].