Research Associate, Genome Engineering

colossalbiosciences; Dallas (TX); On-site; USD 70,000 - 90,000; Full time

Benefits offered by this job

Medical, dental & vision coverage

Excellent paid time off and holidays

Flexible spending accounts (FSA)

Company matched 401k retirement plan

Paid parental leave at 100% salary up 

Education reimbursement

Job summary

Colossal Biosciences is seeking a Research Associate in Dallas, TX to assist in ambitious synthetic biology projects and large-scale genome engineering for conservation and de-extinction efforts. You will work with engineers and biologists to develop tools and workflows for manipulating large DNA fragments and genomes.

The role involves hands-on molecular biology, genome editing workflows, and contributing to project milestones, with relocation assistance available.

Qualifications

• Bachelor’s or Master’s degree in biological sciences, bioengineering, molecular biology, genetics, or related field.
• Hands-on research experience in academia or industry is highly desirable.

Responsibilities

• Support design, development and testing of multiplex genome engineering tools in mammalian cells.
• Perform routine molecular biology workflows including plasmid DNA preparation, PCR, gel electrophoresis, and gel analysis.
• Generate high-throughput assays for the buildout of gene editing workflows.
• Assist with general lab operations: inventory management, preparation of stocks, and equipment maintenance.
• Assess efficiency of genome editing through Sanger/NGS sequencing.
• Work on project milestones and attend lab meetings.
• Prepare progress reports and presentations; maintain thorough lab records.

Skills

Molecular biology

Nucleic acid extraction

Gel electrophoresis

Cloning techniques

PCR

Gibson assembly

Flow cytometry

Sequence analysis

ELN/LIMS familiarity

Mammalian cell culture

Education

Bachelor’s or Master’s degree in biological sciences/Bioengineering/Molecular biology

Tools

SnapGene

Geneious

Job description

An affiliate of Colossal is looking for a talented Research Associate with knowledge and passion for ambitious synthetic biology projects and large-scale genome engineering for species conservation and de-extinction. We will be building tools and methodologies for engineering various cell types, and will develop workflows to manipulate large DNA fragments and genomes. The candidate will work with a talented group of engineers and biologists committed to developing novel technologies that will change the world.

This position will be based out of Dallas, TX. Relocation assistance is available

Duties and Responsibilities:

• Work with senior lab members to support the design, development and testing of multiplex genome engineering tools in mammalian cells
• Perform routine molecular biology workflows, including plasmid DNA preparation (mini/midi/maxi preps), PCR, gel electrophoresis, and gel analysis
• Generate high-throughput assays for the buildout of gene editing workflows
• Assist with general lab operations, such as inventory management, preparation of common stocks, and basic equipment maintenance
• Work with team members to assess efficiency of genome editing through Sanger/NGS sequencing approaches
• Work on project milestones
• Attend lab meetings, prepare progress reports and presentations
• Great organizational skills and excellent laboratory record maintenance
• Learn new techniques as they become available or implemented within the company

Required Skills and Abilities:

• Hands-on experience in molecular biology (nucleic acid and protein extraction, gel electrophoresis) and cloning techniques (restriction enzyme-based cloning, Gibson assembly)
• Preferred experience with with PCR and flow cytometry
• Preferred experience with sequence analysis software (e.g., SnapGene, Geneious)
• Strong written and oral communication skills, as well as creative problem-solving skills.
• Preferred familiarity with electronic lab notebooks (ELN) and laboratory inventory management systems
• Preferred experience with mammalian cell culture

Education and Experience:

• Bachelor's or Master's degree in biological sciences, bioengineering, molecular biology, genetics, or any science related field.
• Prior hands-on research experience in academia or industry is highly desirable.

What Colossal Offers Full-Time Employees:

• Medical, dental, and vision coverage
• Excellent paid time off and company holidays so you can rest and recharge
• Flexible spending accounts (FSA)
• Company matched 401k retirement plan
• Paid parental leave at 100% salary for up to 12 weeks
• Education reimbursement
• An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That's why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.

Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we're doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law

Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.

Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026:

• #1 on the 50 Best Startups to Work For in Dallas in 2023!
• 100 Best Midsize Places to Work in Dallas in 2024 & 2025
• 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026.
• Built In 2026 Award Lists
• Great Place to Work Certification Page
• Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.
• Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!